ID B7GGQ6_ANOFW Unreviewed; 565 AA.
AC B7GGQ6;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Acetyl-coenzyme A synthetase {ECO:0000313|EMBL:ACJ32858.1};
GN OrderedLocusNames=Aflv_0474 {ECO:0000313|EMBL:ACJ32858.1};
OS Anoxybacillus flavithermus (strain DSM 21510 / WK1).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Anoxybacillus.
OX NCBI_TaxID=491915 {ECO:0000313|EMBL:ACJ32858.1, ECO:0000313|Proteomes:UP000000742};
RN [1] {ECO:0000313|EMBL:ACJ32858.1, ECO:0000313|Proteomes:UP000000742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21510 / WK1 {ECO:0000313|Proteomes:UP000000742};
RX PubMed=19014707; DOI=10.1186/gb-2008-9-11-r161;
RA Saw J.H., Mountain B.W., Feng L., Omelchenko M.V., Hou S., Saito J.A.,
RA Stott M.B., Li D., Zhao G., Wu J., Galperin M.Y., Koonin E.V.,
RA Makarova K.S., Wolf Y.I., Rigden D.J., Dunfield P.F., Wang L., Alam M.;
RT "Encapsulated in silica: genome, proteome and physiology of the
RT thermophilic bacterium Anoxybacillus flavithermus WK1.";
RL Genome Biol. 9:R161.1-R161.16(2008).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CP000922; ACJ32858.1; -; Genomic_DNA.
DR AlphaFoldDB; B7GGQ6; -.
DR STRING; 491915.Aflv_0474; -.
DR KEGG; afl:Aflv_0474; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_59_10_9; -.
DR Proteomes; UP000000742; Chromosome.
DR GO; GO:0016878; F:acid-thiol ligase activity; IEA:UniProt.
DR GO; GO:0016405; F:CoA-ligase activity; IEA:UniProt.
DR CDD; cd05972; MACS_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43605:SF10; ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3; 1.
DR PANTHER; PTHR43605; ACYL-COENZYME A SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Reference proteome {ECO:0000313|Proteomes:UP000000742}.
FT DOMAIN 60..420
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 470..549
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 565 AA; 64212 MW; 39330ABF533DA037 CRC64;
MTKLGSSSYR VFIFKIFRKV IQNYSIFLYN FFVSYGKGER KMNLIAPEKY NLTSEFEKYA
DDPNRMALKW ESESGETKEL TYVELMKQAN KIANAFVNHG LQKGDKVLVM LPRLLEAYAV
YIGALKAGLV VIPSSEMLRT KDLQYRISHG EVKGVIAYFL YIEQFIPIEG MENMVAFSVG
GSTERWLDLH EEMAKQSDAF VAVETSREDM AFLSYTSGTT GNPKGVVHTH AWAYAHLRTA
AKNWLCIEEG DLVWATASPG WQKWVWSPFL STLGSGATGF VYYGRFEPEK YLQLLEKYHI
NVLCCTPTEY RLMAKVPTIS QYKLPHLHSA VSAGEPLNRE VIDTFERYFG VQVRDGYGQT
ENTLLVGVMK GMKIKPGSMG KPTPGNRVEI INEFGEPCAV GEVGDIAVHV ETPALFKCYY
KDPERTAMQF RGEYYITGDK AKKDEEGYFW FEGRGDDIII SSGYTIGPFE VEDALVKHPF
VKECAVVASP DEIRGHVVKA FIVLREGVDK NDPNLIPQLQ EHVKQLTAPY KYPRKIEFVD
DLPKTTSGKI RRVELREREM KAMQK
//
