ID C0ZNF2_RHOE4 Unreviewed; 643 AA.
AC C0ZNF2;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN Name=acs {ECO:0000313|EMBL:BAH31204.1};
GN OrderedLocusNames=RER_04960 {ECO:0000313|EMBL:BAH31204.1};
OS Rhodococcus erythropolis (strain PR4 / NBRC 100887).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus; Rhodococcus erythropolis group.
OX NCBI_TaxID=234621 {ECO:0000313|EMBL:BAH31204.1, ECO:0000313|Proteomes:UP000002204};
RN [1] {ECO:0000313|Proteomes:UP000002204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PR4 / NBRC 100887 {ECO:0000313|Proteomes:UP000002204};
RA Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S.,
RA Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.;
RT "Comparison of the complete genome sequences of Rhodococcus erythropolis
RT PR4 and Rhodococcus opacus B4.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BAH31204.1, ECO:0000313|Proteomes:UP000002204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PR4 / NBRC 100887 {ECO:0000313|Proteomes:UP000002204};
RX PubMed=16423019; DOI=10.1111/j.1462-2920.2005.00899.x;
RA Sekine M., Tanikawa S., Omata S., Saito M., Fujisawa T., Tsukatani N.,
RA Tajima T., Sekigawa T., Kosugi H., Matsuo Y., Nishiko R., Imamura K.,
RA Ito M., Narita H., Tago S., Fujita N., Harayama S.;
RT "Sequence analysis of three plasmids harboured in Rhodococcus erythropolis
RT strain PR4.";
RL Environ. Microbiol. 8:334-346(2006).
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DR EMBL; AP008957; BAH31204.1; -; Genomic_DNA.
DR RefSeq; WP_020905977.1; NC_012490.1.
DR AlphaFoldDB; C0ZNF2; -.
DR KEGG; rer:RER_04960; -.
DR PATRIC; fig|234621.6.peg.939; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_3_6_11; -.
DR Proteomes; UP000002204; Chromosome.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:BAH31204.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 29..80
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 86..475
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 531..610
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 643 AA; 69967 MW; 8A4D79100F54D649 CRC64;
MTSAAETDVP QAYPPSAEFA AAANAGPELQ AAADTDRLAF WANQAERLHW HEKWTDVLDW
TDAPVAKWFV GGKLNVAYNC VDRHVLAGNG DRVAIHFEGE PGDSRDLTYN DLLAEVSRAA
NTFTDLGLVA GDRVAIYMPM IPEAIVTMLA CARLGLTHSV VFAGFSATAL RSRIDDAQAK
LVVTVDGQWR RGAAAPIKTA VDESVAGADS VQNVLVVNRT GIDVEWTDGR DLWWHETVAA
ASPEHEAQAF DAEHPLFILY TSGTTGKPKG IIHTSGGYLT QASYTHHNVF DHKAGQDVYW
CTADIGWVTG HSYIVYGPLS NGVTQVVYEG TPNSPNEHRH FDIIEKYGVS IYYTAPTLVR
TFMKWGREIP DAHDLSSIRL LGSVGEPINP EAWRWFRDVI GGNKAPIVDT WWQTETGAIM
ISPLPGITAT KPGSAMAPLP GISAKIVDDD AKPLGPGGNG YLVLDEPWPA MLRGIWGDMD
RYRDTYWSRY AEEGWYFAGD GAKYDDDGAL WVLGRVDDVM NVSGHRISTS EVESALVNHH
GVAEAAVVGA ADETTGQGIV AFVILREGVE NTGEVLIAEL KAQVSTDISP IAKPRQITIV
PELPKTRSGK IMRRLLRDVA EGRDLGDTST LVDPKVFDAI RGK
//
