ID C1CAE6_STRP7 Unreviewed; 638 AA.
AC C1CAE6;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Surface protein PspA {ECO:0000313|EMBL:ACO18024.1};
GN OrderedLocusNames=SP70585_0197 {ECO:0000313|EMBL:ACO18024.1};
OS Streptococcus pneumoniae (strain 70585).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=488221 {ECO:0000313|EMBL:ACO18024.1, ECO:0000313|Proteomes:UP000002211};
RN [1] {ECO:0000313|Proteomes:UP000002211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=70585 {ECO:0000313|Proteomes:UP000002211};
RX PubMed=21034474; DOI=10.1186/gb-2010-11-10-r107;
RA Donati C., Hiller N.L., Tettelin H., Muzzi A., Croucher N.J.,
RA Angiuoli S.V., Oggioni M., Dunning Hotopp J.C., Hu F.Z., Riley D.R.,
RA Covacci A., Mitchell T.J., Bentley S.D., Kilian M., Ehrlich G.D.,
RA Rappuoli R., Moxon E.R., Masignani V.;
RT "Structure and dynamics of the pan-genome of Streptococcus pneumoniae and
RT closely related species.";
RL Genome Biol. 11:R107.1-R107.19(2010).
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DR EMBL; CP000918; ACO18024.1; -; Genomic_DNA.
DR RefSeq; WP_001035336.1; NC_012468.1.
DR AlphaFoldDB; C1CAE6; -.
DR KEGG; snm:SP70585_0197; -.
DR HOGENOM; CLU_013804_1_0_9; -.
DR Proteomes; UP000002211; Chromosome.
DR Gene3D; 6.10.140.920; -; 1.
DR Gene3D; 2.10.270.10; Cholin Binding; 3.
DR Gene3D; 2.20.120.10; Multimodular pneumococcal cell wall endolysin, domain 3; 1.
DR InterPro; IPR018337; Cell_wall/Cho-bd_repeat.
DR NCBIfam; NF033930; pneumo_PspA; 1.
DR Pfam; PF01473; Choline_bind_1; 5.
DR Pfam; PF19127; Choline_bind_3; 2.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SUPFAM; SSF69360; Cell wall binding repeat; 2.
DR SUPFAM; SSF161270; PspA lactotransferrin-binding region; 1.
DR PROSITE; PS51170; CW; 10.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..638
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039551028"
FT REPEAT 400..419
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REPEAT 420..439
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REPEAT 440..459
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REPEAT 460..479
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REPEAT 480..499
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REPEAT 500..519
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REPEAT 520..539
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REPEAT 540..559
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REPEAT 560..579
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REPEAT 580..599
FT /note="Cell wall-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT REGION 33..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 148..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 300..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..91
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..345
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..373
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..397
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 638 AA; 71699 MW; 59F80B14496ECE23 CRC64;
MNKKKMILTS LASVAILGAG FVTSQPTFVR AEEAPVANQS KAEKDYDAAK RDAENAKKAL
EDAKRAQKKY KDDQKITEEK AEEEKKASQE QQKANLDYQQ KLRKYINEKD SKKRSMLQKE
MEEAERKDKE KQAEFKKIRE KVIPSAEELT ETRRKAEEAE AKEPELTKKV KEAEEKVTEA
KQKLDAERAK EVALQAKIAE LENEVHRLET KLKEIDESDS EDYVKEGLRA PLQSELDAKQ
AKLSKLEELS DKIDELDAEI AKLEKDVEDF KNSDGEYSAL YLEAAEKDLA AKKAELEKTE
ADLKKAVNEP EKPAPAPETP APEAPAEQPK PAPAPQPAPA PKPEKPAEQP KPEKTDDQQA
EEDYARRSEE EYNRLTQQQP PKAEKPAPAP QPEQPAPAPK TGWKQENGMW YFYNTDGSMA
TGWLQNNGSW YYLNSNGAMA TGWLQNNGSW YYLNANGAMA TGWLQNNGSW YYLNSNGAMA
TGWLQYNGSW YYLNANGDMA TGWLQNNGSW YYLNANGAMA TGWAKVNSSW YYLNANGAMA
TGWAKVNSSW YYLNANGAMA TGWAKVNGSW YYLNANGSMA TGWVKDGDTW YYLEASGAMK
ASQWFKVSDK WYYVNGLGAL AVNTTVDGYE VNANGEWV
//
