ID C3N9C1_SULIY Unreviewed; 336 AA.
AC C3N9C1;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Alcohol dehydrogenase GroES domain protein {ECO:0000313|EMBL:ACP44583.1};
GN OrderedLocusNames=YG5714_0289 {ECO:0000313|EMBL:ACP44583.1};
OS Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=439386 {ECO:0000313|EMBL:ACP44583.1, ECO:0000313|Proteomes:UP000002308};
RN [1] {ECO:0000313|EMBL:ACP44583.1, ECO:0000313|Proteomes:UP000002308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Y.G.57.14 / Yellowstone #1 {ECO:0000313|Proteomes:UP000002308};
RX PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT "Biogeography of the Sulfolobus islandicus pan-genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
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DR EMBL; CP001403; ACP44583.1; -; Genomic_DNA.
DR RefSeq; WP_010923898.1; NC_012622.1.
DR AlphaFoldDB; C3N9C1; -.
DR GeneID; 8760132; -.
DR KEGG; siy:YG5714_0289; -.
DR HOGENOM; CLU_026673_11_0_2; -.
DR Proteomes; UP000002308; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08259; Zn_ADH5; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR NCBIfam; NF041172; AcrlCoa_red_Thmprot; 1.
DR PANTHER; PTHR42940; ALCOHOL DEHYDROGENASE 1-RELATED; 1.
DR PANTHER; PTHR42940:SF8; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
DR PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 8..332
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 336 AA; 36468 MW; DB00AE2369C49F86 CRC64;
MKAVILPAHK QGYRIEEVPD PKPGKDEAII KVNKAALCYR DLLQIKGFYP RSKYPLILGH
EVVGTVEEVG EDVKDFKKGD RVTSMLFVPD WSCEYCKSGE EVYCKNRVVY AQELDGFFAE
KAKVKASSLV KVPESVSDEG AVIVPCVAAM VYRGLKKAGI KKGEIVLVTG ASGGVGIHAI
QVAKALGAKV IGVTSGESKA KIVSKYADYV IVGEKFSEEA KKIGDVSIVI ENVGPYTLEE
SMKSLRSGGK IIQIGNLDPS VTFNLRLGYI ILKDISLMGH IGANKNDIIK TLNLVKEGKI
KPVIGSEVSL ENFGKALDLL NDSKNRYGKI LISNSF
//
