ID C6XTD0_PEDHD Unreviewed; 632 AA.
AC C6XTD0;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN OrderedLocusNames=Phep_3517 {ECO:0000313|EMBL:ACU05708.1};
OS Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457
OS / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3).
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=485917 {ECO:0000313|EMBL:ACU05708.1, ECO:0000313|Proteomes:UP000000852};
RN [1] {ECO:0000313|EMBL:ACU05708.1, ECO:0000313|Proteomes:UP000000852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 /
RC NCIMB 9290 / NRRL B-14731 / HIM 762-3
RC {ECO:0000313|Proteomes:UP000000852};
RX PubMed=21304637; DOI=10.4056/sigs.22138;
RA Han C., Spring S., Lapidus A., Del Rio T.G., Tice H., Copeland A.,
RA Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S.,
RA Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.C., Saunders E., Chertkov O.,
RA Brettin T., Goker M., Rohde M., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Detter J.C.;
RT "Complete genome sequence of Pedobacter heparinus type strain (HIM 762-
RT 3).";
RL Stand. Genomic Sci. 1:54-62(2009).
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DR EMBL; CP001681; ACU05708.1; -; Genomic_DNA.
DR RefSeq; WP_015809317.1; NZ_AQGK01000001.1.
DR AlphaFoldDB; C6XTD0; -.
DR STRING; 485917.Phep_3517; -.
DR KEGG; phe:Phep_3517; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_3_6_10; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000000852; Chromosome.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ACU05708.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000852}.
FT DOMAIN 9..64
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 66..452
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 514..592
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 632 AA; 70713 MW; 027EEF64F2E0A401 CRC64;
MQIKSFEEYQ KTYQYSVDYP EQFWEGIANN FQWRKKWNKV LSWNFSEPNI KWFEGAKLNI
TENCLDRHLA ENGDKPAIIW EPNDPQKESI TLSYKILHEQ VCRFGNVLKK NGVKKGDRVC
IYMPMVPELA VAVLACARIG AVHSVVFGGF SAKSIADRIN DAECKVVITA DGAFRGNKQI
QLKEVIDDAL IGCPTVERVI VLTHTRMAVS MLKGRDVWWE DEIKLVDTNC PAEEMDAEDL
LFILYTSGST GKPKGVVHTI GGYMVYAGYT FSNVFNYQPD EVFFCTADIG WITGHSYIVY
GPLSQGATTL MFEGIPTFPD ASRMWQVVEK HKVNILYTAP TAIRSLMSFG EEPLKGIDLS
SLRVLGSVGE PINEEAWHWF DENIGKSKCP IVDTWWQTET GGIMISPIAY VTPTKPSFAT
LPLPGIQPML VDEQGKEIEG NGVNGNLCIK FPWPGMLRTT YGDHERCKLT YFSTYKDLYF
TGDGCLRDED GYYRITGRVD DVINVSGHRI GTAEVENAIN MHAGVVESAV VGYPHDVKGQ
GIYAFVINPN VHNDEDLTRK DILQTVTRVI GAIAKPDKIL FVSGLPKTRS GKIMRRILRK
IAEGETSQIG DTSTLLDPAV VTEIIEKAGQ LK
//
