ID D2GXB2_AILME Unreviewed; 651 AA.
AC D2GXB2;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 24-JAN-2024, entry version 86.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFB15791.1};
DE Flags: Fragment;
GN ORFNames=PANDA_001525 {ECO:0000313|EMBL:EFB15791.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB15791.1};
RN [1] {ECO:0000313|EMBL:EFB15791.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
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DR EMBL; GL192367; EFB15791.1; -; Genomic_DNA.
DR RefSeq; XP_002913703.1; XM_002913657.3.
DR AlphaFoldDB; D2GXB2; -.
DR STRING; 9646.ENSAMEP00000002467; -.
DR GeneID; 100479145; -.
DR KEGG; aml:100479145; -.
DR CTD; 79411; -.
DR eggNOG; KOG0496; Eukaryota.
DR HOGENOM; CLU_007853_7_2_1; -.
DR InParanoid; D2GXB2; -.
DR OMA; HERQYLH; -.
DR OrthoDB; 5489808at2759; -.
DR TreeFam; TF314816; -.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR PANTHER; PTHR23421:SF50; BETA-GALACTOSIDASE-1-LIKE PROTEIN; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..651
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015088172"
FT DOMAIN 38..353
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 400..512
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 537..592
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 185
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 263
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT NON_TER 651
FT /evidence="ECO:0000313|EMBL:EFB15791.1"
SQ SEQUENCE 651 AA; 73997 MW; 9B31321D7214F355 CRC64;
MAPEKPLCLP ALLLPLLTLL LPQADTRSFV VDRENDRFLL DGVPFRYVSG SLHYFRVPRV
LWADRLFKMR MSGLNTVQFY VPWNYHEPEP GVYNFNGSRD LFAFLNEASV ANLLVILRPG
PYICAEWDMG GLPAWLLQKP DIHLRTSDPD FLAAVDSWFK VLLPRLYPWL YHNGGNIISV
QVENEYGSYR ACDFGYMRHL AGLFRALLGD RILLFTTDGP EGLKCGSLQG LYTTVDFGPA
DNMTKIFALL RKYEPHGPLV NSEYYTGWLD YWGQNHSMRS ILAVTTGLEN MLRLGASVNM
YMFHGGTNFG YWNGADEKGR FLPITTSYDY DAPISEAGDP TPKLFALRNV ISKFQEIPLG
PLPPPSPKMM LGPLTLHLDG DLLAFLDFLC PQGPIRSILP LPFEAVKQDR GFVLYRTYLT
YTVSEPTQFW VPNNGVHDRA YVMVDGVFQG VLERNMKHQL FLMGTVGAKL DILLENMGRL
SFGSNSSDFK GLLEPPILGQ RVLTQWLMFP LKVDKLVKWW FPLQLMKRSH PQVPSGPTFY
STTFPILGEG RDTFLFLPGW TKGQVWINGF NLGRYWTKRG PQETLYVPRP LLFSRGALNK
ITLLELENVP PQPQIQFLDR PILNSTLHKT YIYSLSPDTQ SASEPMELSG H
//
