ID   D3UJB7_HELM1            Unreviewed;       883 AA.
AC   D3UJB7;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00022419};
GN   Name=ppc {ECO:0000313|EMBL:CBG40592.1};
GN   OrderedLocusNames=HMU13380 {ECO:0000313|EMBL:CBG40592.1};
OS   Helicobacter mustelae (strain ATCC 43772 / LMG 18044 / NCTC 12198 / 12198)
OS   (Campylobacter mustelae).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=679897 {ECO:0000313|EMBL:CBG40592.1, ECO:0000313|Proteomes:UP000001522};
RN   [1] {ECO:0000313|EMBL:CBG40592.1, ECO:0000313|Proteomes:UP000001522}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43772 / LMG 18044 / NCTC 12198 / 12198
RC   {ECO:0000313|Proteomes:UP000001522};
RX   PubMed=20219135; DOI=10.1186/1471-2164-11-164;
RA   O'Toole P.W., Snelling W.J., Canchaya C., Forde B.M., Hardie K.R.,
RA   Josenhans C., Graham R.L.J., McMullan G., Parkhill J., Belda E.,
RA   Bentley S.D.;
RT   "Comparative genomics and proteomics of Helicobacter mustelae, an
RT   ulcerogenic and carcinogenic gastric pathogen.";
RL   BMC Genomics 11:164-164(2010).
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC       for the tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003670}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC         phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC         Evidence={ECO:0000256|ARBA:ARBA00001071};
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DR   EMBL; FN555004; CBG40592.1; -; Genomic_DNA.
DR   RefSeq; WP_013023659.1; NC_013949.1.
DR   AlphaFoldDB; D3UJB7; -.
DR   STRING; 679897.HMU13380; -.
DR   KEGG; hms:HMU13380; -.
DR   eggNOG; COG2352; Bacteria.
DR   HOGENOM; CLU_006557_2_0_7; -.
DR   Proteomes; UP000001522; Chromosome.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:InterPro.
DR   GO; GO:0015977; P:carbon fixation; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   PANTHER; PTHR30523:SF6; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:CBG40592.1};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Pyruvate {ECO:0000313|EMBL:CBG40592.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001522}.
FT   ACT_SITE        121
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10111"
FT   ACT_SITE        535
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10112"
SQ   SEQUENCE   883 AA;  101662 MW;  E82553640A510C71 CRC64;
     MSDFEREKQF IMELMRKMLQ STDALAAEFF DAFILALNKQ ECTSSLLTQI IQNNKTLEVI
     KAFSLYNILL NIIQERYNIK TAKPLQKIAQ TYEELIAQGF DPEDIQEIIN KMEFYPVFTA
     HPTESRRRTF LEAHYAINRD LHKIFELHDE ELIEDINYRL HLLWRTHLVR SQKLEVLFEL
     DNLLYIIETS ILNSAQKTLN MLSALLPKPL SKSPIRLGSW IGGDRDGNPF VSNELMTQVM
     KTQHKLLINL YIKKVEKLIR ELSISQDFCN ISEELLRSIQ REKEHLDSFR LYSKEPFRTK
     LFLIKKKLQN RFIGINTNWR EEFVYHSAKE LLADIDLLID SAPEHCTRSL KEFRNLVLLA
     DFSLLHLDFR EHKSVFQEAI SEIFCLLGMC DNDFGSLSEE KKIEILNQAL DSPKSILSEI
     LPSLSRDTQN VIEIFVSIAW GKRHISEEIL HSFILSMTTD ASDLLTILWF IKQNRLWIPG
     QSAQIAITPL FETIQDLKHS KEILLTLSKN PHYSLYLKDC ASTQEIMVGY SDSSKDGGIF
     ASNYNLHSAI YDLIKLGESL KITFKLFHGR GGSVSRGGGT LESALLAAPP RSVNGMLKVT
     EQGEIIGSKY LSPMSADFNF ANTLSALLKK SCLDAFCTHD IAHDDLDAKM CEITRSHRGQ
     MQKISEQSYL KYRELVYGTA GFMDYFKAAT PIEFIQQLNL GSRPSKRKDT AKVEDLRAIP
     WVFAWTQNRS IIPAWYGLGS GLLAIEDKNA LRQSYLESDF FRATIDNISQ AFLKVDLEIA
     GFYNAFIDDE ALGNKIWGMI AEEYDKTMEY ILWIRDESEL LCSQPEIRKS ILMRKPTVNA
     LNLLQIELIK RYQKSHYEKQ KTRLLEEIHS TIIGIAQGLR NTG
//