ID E2BDA9_HARSA Unreviewed; 529 AA.
AC E2BDA9;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 28-JUN-2023, entry version 47.
DE RecName: Full=aldehyde dehydrogenase (NAD(+)) {ECO:0000256|ARBA:ARBA00024226};
DE EC=1.2.1.3 {ECO:0000256|ARBA:ARBA00024226};
GN ORFNames=EAI_15605 {ECO:0000313|EMBL:EFN86337.1};
OS Harpegnathos saltator (Jerdon's jumping ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Harpegnathos.
OX NCBI_TaxID=610380 {ECO:0000313|Proteomes:UP000008237};
RN [1] {ECO:0000313|EMBL:EFN86337.1, ECO:0000313|Proteomes:UP000008237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R22 G/1 {ECO:0000313|EMBL:EFN86337.1,
RC ECO:0000313|Proteomes:UP000008237};
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
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DR EMBL; GL447585; EFN86337.1; -; Genomic_DNA.
DR RefSeq; XP_011136683.1; XM_011138381.2.
DR AlphaFoldDB; E2BDA9; -.
DR STRING; 610380.E2BDA9; -.
DR EnsemblMetazoa; XM_011138381.3; XP_011136683.1; LOC105181543.
DR GeneID; 105181543; -.
DR KEGG; hst:105181543; -.
DR InParanoid; E2BDA9; -.
DR OMA; DAWKVYM; -.
DR OrthoDB; 8449at2759; -.
DR PhylomeDB; E2BDA9; -.
DR Proteomes; UP000008237; Unassembled WGS sequence.
DR GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR CDD; cd07130; ALDH_F7_AASADH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR044638; ALDH7A1-like.
DR PANTHER; PTHR43521; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43521:SF1; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000008237}.
FT DOMAIN 51..511
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 284
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 529 AA; 56620 MW; 935C4073C73CE00C CRC64;
MASLLLKKVR NISQFQMARH LVTDPKYGFL KELGITAVNP GLYDGKWGGS GEVIESISPV
TGKVIAKVRQ STPQEASNAI TEARKAWSQW ASIPAPARGE IVRQIGDELR KNLKPLGCLV
SLEMGKILPE GIGEVQEFID ICDYAVGLSR MLPGNVFPSE RKDHALLEKW NPLGVVGVIS
AFNFPIAVYG WNTAIAMVCG NAIVWKGAST TPLVAIATTK IISAVLERNG IPGSVASLVS
GGPDVGETLV NDKRIPLVSF TGSTNVGRQV AVKVQQRFGR SLLELGGNNA LIVAEDADLE
MAVRAAVFSC VGTAGQRCTT TRRLILHQKI KQEFLGKLKT AYKSILARIG DPLDDGVLYG
PMHNQKGVDE YLQAIKKAVE AGGTIEFGGK QVKRPGYYVE PTIISGLRAD TEVVQQETFA
PIVYILEANS LEEAINLNNG VEQGLSSSLF TKSIGNVFQW IGPHGSDCGI VNVNIGTSGA
EIGGAFGGEK ATGGGRESGS DAWKHYMRRA TITINHGNEL PLAQGIKFE
//
