ID   F4CUF0_PSEUX            Unreviewed;       602 AA.
AC   F4CUF0;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   24-JAN-2024, entry version 57.
DE   RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE            EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN   OrderedLocusNames=Psed_3144 {ECO:0000313|EMBL:AEA25340.1};
OS   Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 /
OS   CB1190).
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Pseudonocardia.
OX   NCBI_TaxID=675635 {ECO:0000313|EMBL:AEA25340.1, ECO:0000313|Proteomes:UP000007809};
RN   [1] {ECO:0000313|EMBL:AEA25340.1, ECO:0000313|Proteomes:UP000007809}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 55486 / DSM 44775 / JCM 13855 / CB1190
RC   {ECO:0000313|Proteomes:UP000007809};
RX   PubMed=21725009; DOI=10.1128/JB.00415-11;
RA   Sales C.M., Mahendra S., Grostern A., Parales R.E., Goodwin L.A., Woyke T.,
RA   Nolan M., Lapidus A., Chertkov O., Ovchinnikova G., Sczyrba A.,
RA   Alvarez-Cohen L.;
RT   "Genome sequence of the 1,4-dioxane-degrading Pseudonocardia dioxanivorans
RT   strain CB1190.";
RL   J. Bacteriol. 193:4549-4550(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC         (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC         diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR   EMBL; CP002593; AEA25340.1; -; Genomic_DNA.
DR   RefSeq; WP_013675261.1; NC_015312.1.
DR   AlphaFoldDB; F4CUF0; -.
DR   STRING; 675635.Psed_3144; -.
DR   KEGG; pdx:Psed_3144; -.
DR   eggNOG; COG1793; Bacteria.
DR   eggNOG; COG3275; Bacteria.
DR   HOGENOM; CLU_453326_0_0_11; -.
DR   Proteomes; UP000007809; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd07906; Adenylation_DNA_ligase_LigD_LigC; 1.
DR   CDD; cd07971; OBF_DNA_ligase_LigD; 1.
DR   Gene3D; 3.30.1490.70; -; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR   PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR   PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF06580; His_kinase; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:AEA25340.1};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007809};
KW   Transferase {ECO:0000313|EMBL:AEA25340.1}.
FT   DOMAIN          110..249
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50160"
FT   REGION          319..448
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   602 AA;  63410 MW;  6A76D77FE8E089A7 CRC64;
     MVRAGTGGMP ELVPPMLAAS GDLPTGPGWA VEFAWDGLRC IAYARPGRVR LLTARDRSVS
     STFPELHVLA AKAPRQGVIL DGTVVALDDA GIPSRRMLMR RTATQRPGAA LVAEVPVGFF
     VSDLVWLDGE STTSLPYRRR RELIDDLGLA EQPVVLSPSW PAGDAGHVLA TARRYGLDGV
     FAKRLDSAYQ PGRRSRNWLR VPLRRSRQVV VGGWTPASAD RPDSVAALLL GVPGPEGLRY
     VGRAGVGAGT DRAAVTALVP DLHSDSSPFV GEVPASVARD AMWVVPRLVG LVEFTEWTMG
     GRLRLPVWRG LVTPEEVDDA LWDDGPDLDG PAAGRPAADG PDADRPAADG PGADRAVSDR
     AVTDRAVTDR AATARTPVDR PNGGRPESDR ATDLRANGDG ATGDGATGDG ATGDGANLDR
     ERGDRTGAGT AAEQAPPGPG AGAAPAALPS EARVHARRLE QHFVYNSLNT IASLVRTDPG
     RARDLLLGFA DLTRAADRPA EETIGLRDEL DTVRAYLELE RARFGKRLTA SVTTDEGLDD
     VPVVPLSVLV RVRSVVQEVV EPRPGGGAVS VHAAMEGSTC VVTVAEEATA QRWTVPVAPA
     QV
//