ID G8MYN1_GEOTH Unreviewed; 378 AA.
AC G8MYN1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Putative zinc-type alcohol dehydrogenase-like protein AdhB {ECO:0000313|EMBL:AEV18428.1};
GN ORFNames=GTCCBUS3UF5_11120 {ECO:0000313|EMBL:AEV18428.1};
OS Geobacillus thermoleovorans CCB_US3_UF5.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC Geobacillus thermoleovorans group.
OX NCBI_TaxID=1111068 {ECO:0000313|EMBL:AEV18428.1, ECO:0000313|Proteomes:UP000005636};
RN [1] {ECO:0000313|EMBL:AEV18428.1, ECO:0000313|Proteomes:UP000005636}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCB_US3_UF5 {ECO:0000313|EMBL:AEV18428.1,
RC ECO:0000313|Proteomes:UP000005636};
RA Muhd Sakaff M.K.L., Abdul Rahman A.Y., Saito J.A., Hou S., Alam M.;
RT "Complete genome sequence of thermophilic Geobacillus thermoleovorans
RT CCB_US3_UF5.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; CP003125; AEV18428.1; -; Genomic_DNA.
DR RefSeq; WP_011230439.1; NC_016593.1.
DR AlphaFoldDB; G8MYN1; -.
DR KEGG; gte:GTCCBUS3UF5_11120; -.
DR PATRIC; fig|1111068.3.peg.1072; -.
DR HOGENOM; CLU_026673_11_3_9; -.
DR Proteomes; UP000005636; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08283; FDH_like_1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 26..140
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 189..257
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 378 AA; 41358 MW; 633CDA09019E006C CRC64;
MKAVTYQGIK DVAVKQMPDP KILKDDDIIV KITSTAICGS DLHLVHGMIP NMPEDFIIGH
EPMGIVEEVG PAVTKVKKGD RVIVPFTIAC GQCWYCQHGL ESQCDASNPN GESGGYFGYS
ETFGGYPGGQ AEYLRVPFAN FTPFVVPENC ELEDEKLLFL SDIIPTAFWG VDEAGVKDGD
TVVVLGCGPV GLLTQKFAWM KGAKRVIAVD YIDYRIEHAK KTNKVETLNF TEYENVGEYI
KEMTGGGADV VIDCVGLDGK MTPLELIGSA LKLQGGAMGA IVIASQAVRK GGTIQLVGVY
GARYNQFPLG DLFSRNITLK MGQAPVIHYI PTLYEWIVEG KFDPTDIITH RLPLDEAQYA
YEIFDEKKDG CIKVVLKP
//
