ID H3ZL62_THELN Unreviewed; 320 AA.
AC H3ZL62;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 2.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=2-ketoisovalerate ferredoxin oxidoreductase subunit beta {ECO:0000313|EMBL:EHR79312.2};
DE EC=1.2.7.7 {ECO:0000313|EMBL:EHR79312.2};
GN ORFNames=OCC_07486 {ECO:0000313|EMBL:EHR79312.2};
OS Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=523849 {ECO:0000313|EMBL:EHR79312.2, ECO:0000313|Proteomes:UP000015502};
RN [1] {ECO:0000313|EMBL:EHR79312.2, ECO:0000313|Proteomes:UP000015502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51850 / DSM 5473 / JCM 8560 / NS-C
RC {ECO:0000313|Proteomes:UP000015502};
RX PubMed=22493191; DOI=10.1128/JB.00123-12;
RA Gardner A.F., Kumar S., Perler F.B.;
RT "Genome sequence of the model hyperthermophilic archaeon Thermococcus
RT litoralis NS-C.";
RL J. Bacteriol. 194:2375-2376(2012).
CC -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma
CC chain. {ECO:0000256|ARBA:ARBA00011595}.
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DR EMBL; CP006670; EHR79312.2; -; Genomic_DNA.
DR AlphaFoldDB; H3ZL62; -.
DR STRING; 523849.OCC_07486; -.
DR PaxDb; 523849-OCC_07486; -.
DR KEGG; tlt:OCC_07486; -.
DR HOGENOM; CLU_058423_0_0_2; -.
DR Proteomes; UP000015502; Chromosome.
DR GO; GO:0043807; F:3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity; IEA:UniProtKB-EC.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR CDD; cd03376; TPP_PFOR_porB_like; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR42897; PYRUVATE SYNTHASE SUBUNIT PORB; 1.
DR PANTHER; PTHR42897:SF2; PYRUVATE SYNTHASE SUBUNIT PORB; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EHR79312.2}.
FT DOMAIN 81..227
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 320 AA; 35664 MW; 2B89FB8CDCE9117B CRC64;
MVPLEEVRKM ELPADVKKRL TLPFEEHFYA GHTACQGCGA SLGLRYVLKA YGGKAIFTIP
ACCSTIIAGP WPYTALNAPL FHTAFETTGA VISGIEAALK AKGYKVKGED GIMVIGWAGD
GGTADIGLQA LSGFLERGHD ALYIMYDNEA YMNTGIQRSS STPYGAWTTN TPGGKKHFLE
QRPKKKVIDI VIAHKPAYAA TASIAYPEDF MRKLKKAQTI KGPSFIQLFA PCPTGWRSPT
DKTIELARLA VQTAYFPLFE YENGKYKINM PSPNKEPKPL EEYLKLQGRF KYMTKEDMEI
LQEWVLKEWE ELKKKAELFG
//
