ID H8MUP4_CORCM Unreviewed; 960 AA.
AC H8MUP4;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=oxoglutarate dehydrogenase (succinyl-transferring) {ECO:0000256|ARBA:ARBA00012280};
DE EC=1.2.4.2 {ECO:0000256|ARBA:ARBA00012280};
GN Name=sucA {ECO:0000313|EMBL:AFE10431.1};
GN OrderedLocusNames=COCOR_06569 {ECO:0000313|EMBL:AFE10431.1};
OS Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2)
OS (Myxococcus coralloides).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Corallococcus.
OX NCBI_TaxID=1144275 {ECO:0000313|EMBL:AFE10431.1, ECO:0000313|Proteomes:UP000007587};
RN [1] {ECO:0000313|EMBL:AFE10431.1, ECO:0000313|Proteomes:UP000007587}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25202 / DSM 2259 / NBRC 100086 / M2
RC {ECO:0000313|Proteomes:UP000007587};
RX PubMed=22582372; DOI=10.1128/JB.00397-12;
RA Huntley S., Zhang Y., Treuner-Lange A., Kneip S., Sensen C.W.,
RA Sogaard-Andersen L.;
RT "Complete Genome Sequence of the Fruiting Myxobacterium Corallococcus
RT coralloides DSM 2259.";
RL J. Bacteriol. 194:3012-3013(2012).
RN [2] {ECO:0000313|Proteomes:UP000007587}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25202 / DSM 2259 / NBRC 100086 / M2
RC {ECO:0000313|Proteomes:UP000007587};
RA Huntley S., Zhang Y., Treuner-Lange A., Sensen C.W., Sogaard-Andersen L.;
RT "Genome sequence of the fruiting myxobacterium Corallococcus coralloides
RT DSM 2259.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; CP003389; AFE10431.1; -; Genomic_DNA.
DR RefSeq; WP_014399357.1; NC_017030.1.
DR AlphaFoldDB; H8MUP4; -.
DR STRING; 1144275.COCOR_06569; -.
DR KEGG; ccx:COCOR_06569; -.
DR eggNOG; COG0567; Bacteria.
DR HOGENOM; CLU_004709_1_0_7; -.
DR InParanoid; H8MUP4; -.
DR OrthoDB; 9759785at2; -.
DR Proteomes; UP000007587; Chromosome.
DR GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:UniProtKB-EC.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR CDD; cd02016; TPP_E1_OGDC_like; 1.
DR Gene3D; 3.40.50.12470; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR Gene3D; 3.40.50.11610; Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain; 1.
DR Gene3D; 1.10.287.1150; TPP helical domain; 1.
DR InterPro; IPR032106; 2-oxogl_dehyd_N.
DR InterPro; IPR011603; 2oxoglutarate_DH_E1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR031717; KGD_C.
DR InterPro; IPR042179; KGD_C_sf.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR NCBIfam; TIGR00239; 2oxo_dh_E1; 1.
DR PANTHER; PTHR23152:SF4; 2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1; 1.
DR PANTHER; PTHR23152; 2-OXOGLUTARATE DEHYDROGENASE; 1.
DR Pfam; PF16078; 2-oxogl_dehyd_N; 1.
DR Pfam; PF00676; E1_dh; 1.
DR Pfam; PF16870; OxoGdeHyase_C; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR PIRSF; PIRSF000157; Oxoglu_dh_E1; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000007587};
KW Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052}.
FT DOMAIN 609..802
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 960 AA; 106633 MW; 0CFC06CEA8441005 CRC64;
MANFQDSFLS GGNIDFIEGL YARFLEDPGS VDASWREVFE RNDGTGRPIF NTKLLEAPTP
AAPEGKGKGK ANGAAVQAAA AAPQAPAAPA QDIGLQSKVD QAITAFRLRG HLRAKLDPLA
RPRPQLGHVA DVALMDENHF TPKELEQAVE CNNVFPQQRV RLADLVTRLR RTYSDHIGVE
FMQMLDSERR RWLMKRMEHS DNRTPFSVEE QRHILTKLSY AEGFENFLHT KYVGAKRFSL
DGGEALIPML DALLEVGSGM GLKELVIGMA HRGRLNVLTN ILGKKPDQIF SEFDGPKDPK
AYLGRGDVKY HMGFSSDHAT RSGKNVHLSL AFNPSHLECV GPVVEGRVRA KQDRGGDTER
TQVMPLLIHG DAAFIGQGIT SETLNFSGLK GYTTGGTVHI VINNQVGFTT DPSDSRTSIY
STAIAQMLDI PVFHVNGDDP EACVHAARLA AEYRQTFKSD VVIDLICYRR YGHNEGDDPS
FTQPAMYDLI RKHPPVRALY AKALAEAGRI SAEDSDAIKQ RCFQDFDAAL TRARQESQFK
EPNALEGLWQ PYKGGLLKNA PQASTAVAKA TLRDALQKLA TAPEGFNVHR DVERTVLKKR
QGMLESEELQ WSEGESLAYA TLLSEGYGIR LSGQDSERGT FSHRHAVLHD TQTGEEFTPL
RQFATGKATF NVYNSPLSEM GVLGFDYGYS LDVPDGLTLW EAQFGDFANG AQIIIDQFIA
AAESKWRRLS GITLLLPHGY EGQGPEHSSA RLERFLDLCA EDNLQVCYPT TPAQIFHLLR
RQVLRPVRKP LVIMSPKSLL RRPEATSRMD DLATGAFQEV IPDAKADAAK VKRLLLCSGK
VYYDLAKARD ERKDDSIAIV RVEQLYPFPQ DELANLVAKL PALQELYWVQ EEPRNAGAWH
FMFPRLHDLL SGRSQQQTVK LGYIGRAEAA SPATGFTKTH DYEQQLIIEE AILRGPQNGR
//
