ID I1IGR7_BRADI Unreviewed; 464 AA.
AC I1IGR7;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE RecName: Full=protein-synthesizing GTPase {ECO:0000256|ARBA:ARBA00011986};
DE EC=3.6.5.3 {ECO:0000256|ARBA:ARBA00011986};
GN Name=100837926 {ECO:0000313|EnsemblPlants:KQJ85959};
GN ORFNames=BRADI_4g02587v3 {ECO:0000313|EMBL:KQJ85959.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQJ85959.1};
RN [1] {ECO:0000313|EMBL:KQJ85959.1, ECO:0000313|EnsemblPlants:KQJ85959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ85959.1,
RC ECO:0000313|EnsemblPlants:KQJ85959};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQJ85959.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ85959.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQJ85959}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ85959};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; EC=3.6.5.3;
CC Evidence={ECO:0000256|ARBA:ARBA00001874};
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DR EMBL; CM000883; KQJ85959.1; -; Genomic_DNA.
DR RefSeq; XP_003577708.1; XM_003577660.3.
DR AlphaFoldDB; I1IGR7; -.
DR STRING; 15368.I1IGR7; -.
DR EnsemblPlants; KQJ85959; KQJ85959; BRADI_4g02587v3.
DR GeneID; 100837926; -.
DR Gramene; KQJ85959; KQJ85959; BRADI_4g02587v3.
DR KEGG; bdi:100837926; -.
DR eggNOG; KOG0466; Eukaryota.
DR HOGENOM; CLU_027154_0_1_1; -.
DR InParanoid; I1IGR7; -.
DR OMA; NIGMVGH; -.
DR OrthoDB; 1512042at2759; -.
DR Proteomes; UP000008810; Chromosome 4.
DR ExpressionAtlas; I1IGR7; baseline.
DR GO; GO:0005850; C:eukaryotic translation initiation factor 2 complex; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0001731; P:formation of translation preinitiation complex; IBA:GO_Central.
DR CDD; cd01888; eIF2_gamma; 1.
DR CDD; cd03688; eIF2_gamma_II; 1.
DR CDD; cd15490; eIF2_gamma_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015256; eIF2g_C.
DR InterPro; IPR044127; eIF2g_dom_2.
DR InterPro; IPR044128; eIF2g_GTP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR PANTHER; PTHR42854; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER; 1.
DR PANTHER; PTHR42854:SF3; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED; 1.
DR Pfam; PF09173; eIF2_C; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT DOMAIN 30..239
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 464 AA; 50663 MW; 1C965DBD0B4DDD76 CRC64;
MARRGLMEQD LTKLDVAKLH PLSPEVISRQ ATINIGTIGH VAHGKSTVVK AISGVQTVRF
KNELERNITI KLGYANAKIY KCEDDRCPRP MCYKAYGSGK EDTPICDVPG FENTRMKLLR
HVSFVDCPGH DILMATMLNG AAIMDGALLL IAANESCPQP QTSEHLAAVE IMRLQHLIIL
QNKIDLIQES AAMNQHEAIQ KFIQGTIAEG APVVPISAQL KYNIDVICEY IVKKIPIPER
NFTSPPNMIV IRSFDVNKPG SEVDDIRGGV AGGSILRGVL RVNQNIEVRP GIVMKDESGN
IKCTPIYSRI VSLYAEQNEL QFAVPGGLIG VGTTMDPTLT RADRLVGQVL GEIGSLPDVF
VELEINFFLL RRLLGVRTKG TEKAGKVSKL TKGEILMLNI GSMSTGARVV AVKNDLAKLQ
LTAPVCTSKG EKVALSRRVE KHWRLIGWGQ IQAGATLEVP PCPL
//
