ID I3VTA8_THESW Unreviewed; 337 AA.
AC I3VTA8;
DT 05-SEP-2012, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:AFK85753.1};
GN OrderedLocusNames=Tsac_0731 {ECO:0000313|EMBL:AFK85753.1};
OS Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacterium.
OX NCBI_TaxID=1094508 {ECO:0000313|EMBL:AFK85753.1, ECO:0000313|Proteomes:UP000006178};
RN [1] {ECO:0000313|Proteomes:UP000006178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8691 / JW/SL-YS485 {ECO:0000313|Proteomes:UP000006178};
RA Brown S.D., Land M.L., Herring C.D.;
RT "Thermoanaerobacterium saccharolyticum JW/SL-YS485.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFK85753.1, ECO:0000313|Proteomes:UP000006178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8691 / JW/SL-YS485 {ECO:0000313|Proteomes:UP000006178};
RX PubMed=24907337; DOI=10.1128/AEM.00998-14;
RA Currie D.H., Guss A.M., Herring C.D., Giannone R.J., Johnson C.M.,
RA Lankford P.K., Brown S.D., Hettich R.L., Lynd L.R.;
RT "Profile of Secreted Hydrolases, Associated Proteins, and SlpA in
RT Thermoanaerobacterium saccharolyticum during the Degradation of
RT Hemicellulose.";
RL Appl. Environ. Microbiol. 80:5001-5011(2014).
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DR EMBL; CP003184; AFK85753.1; -; Genomic_DNA.
DR RefSeq; WP_013786963.1; NC_017992.1.
DR AlphaFoldDB; I3VTA8; -.
DR STRING; 1094508.Tsac_0731; -.
DR KEGG; tsh:Tsac_0731; -.
DR PATRIC; fig|1094508.3.peg.738; -.
DR eggNOG; COG1609; Bacteria.
DR BioCyc; TSAC1094508:GLMA-741-MONOMER; -.
DR Proteomes; UP000006178; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06294; PBP1_MalR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..57
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 337 AA; 37623 MW; 2A59638E34518B9F CRC64;
MNVTIKDVAQ RAHVAPSTVS RVIADNPRIS KETKERVFKA MEELGYYPNA IARSLASKMT
YTIGLIMPRS AEDAFSNPFF PEVMRGISVV AHNEKYDLLI STSGNEEEEK QAVIDMVKGR
RVDGIVLLCS RTTDELIPWL REEKFPFTVI GKPLDSKGVC WVDNDNIGAS RLATNYLIKH
GHREIAFISG SLEFVVSLDR LDGYKLALEE NNIPFDKELV AQDEFSEDGG YNAMMRILKQ
KKPTAVVVTD DIMSFGVIRA AIDYGLKVPQ DVSLIGFNNI PLSAYANPPL TTIDISTFDL
GVKSAELLLK NIKNKDFVAD HIIVPVKLIE RKSCIKR
//
