ID   I7FE75_MYCS2            Unreviewed;       296 AA.
AC   I7FE75;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Carbon monoxide dehydrogenase, medium subunit {ECO:0000313|EMBL:AFP37208.1};
DE            EC=1.2.99.2 {ECO:0000313|EMBL:AFP37208.1};
GN   OrderedLocusNames=MSMEI_0728 {ECO:0000313|EMBL:AFP37208.1};
OS   Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS   smegmatis).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=246196 {ECO:0000313|EMBL:AFP37208.1, ECO:0000313|Proteomes:UP000006158};
RN   [1] {ECO:0000313|EMBL:AFP37208.1, ECO:0000313|Proteomes:UP000006158}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000006158};
RX   PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
RA   Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
RA   Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.M.;
RT   "Interrupted coding sequences in Mycobacterium smegmatis: authentic
RT   mutations or sequencing errors?";
RL   Genome Biol. 8:R20.1-R20.9(2007).
RN   [2] {ECO:0000313|EMBL:AFP37208.1, ECO:0000313|Proteomes:UP000006158}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000006158};
RX   PubMed=18955433; DOI=10.1101/gr.081901.108;
RA   Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.M.,
RA   Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
RT   "Ortho-proteogenomics: multiple proteomes investigation through orthology
RT   and a new MS-based protocol.";
RL   Genome Res. 19:128-135(2009).
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DR   EMBL; CP001663; AFP37208.1; -; Genomic_DNA.
DR   RefSeq; WP_003892164.1; NZ_SIJM01000036.1.
DR   RefSeq; YP_885150.1; NC_008596.1.
DR   AlphaFoldDB; I7FE75; -.
DR   GeneID; 66738919; -.
DR   KEGG; msg:MSMEI_0728; -.
DR   OrthoDB; 9793944at2; -.
DR   Proteomes; UP000006158; Chromosome.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.30.390.50; CO dehydrogenase flavoprotein, C-terminal domain; 1.
DR   Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR   InterPro; IPR005107; CO_DH_flav_C.
DR   InterPro; IPR036683; CO_DH_flav_C_dom_sf.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR002346; Mopterin_DH_FAD-bd.
DR   PANTHER; PTHR42659; XANTHINE DEHYDROGENASE SUBUNIT C-RELATED; 1.
DR   PANTHER; PTHR42659:SF2; XANTHINE DEHYDROGENASE SUBUNIT C-RELATED; 1.
DR   Pfam; PF03450; CO_deh_flav_C; 1.
DR   Pfam; PF00941; FAD_binding_5; 1.
DR   SMART; SM01092; CO_deh_flav_C; 1.
DR   SUPFAM; SSF55447; CO dehydrogenase flavoprotein C-terminal domain-like; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000313|EMBL:AFP37208.1}.
FT   DOMAIN          2..179
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
SQ   SEQUENCE   296 AA;  31673 MW;  36C68E11BD7D72C7 CRC64;
     MQVPGPFEYE RATSVDHAVG LLDRLGEDAR IVAGGHSLLP MMKLRIANPE YLVDINDLAV
     ELGYVITDPT LVRIGAMARH RQVLESDPLA AVCPIFRDAE RVIADPVVRN RGTLGGSLCQ
     ADPAEDLTTV CTILGAVCLA RGPGGEREIG IDDFLVGPYE TALAHNEMLV EVRIPVRHRT
     SSAYAKVERR VGDWAVTAAG AQVTLDGDSI VAARVGLTAV NPDPDALRAL ADDLIGKPAT
     EETFAAAGEL AVQACEPVTD TRGSADYKRH LARELTIRTM RTAVERVRTA PAPEGN
//

ID   A0QQG2_MYCS2            Unreviewed;       296 AA.
AC   A0QQG2;
DT   09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2007, sequence version 1.
DT   27-MAR-2024, entry version 114.
DE   SubName: Full=Carbon monoxide dehydrogenase medium chain {ECO:0000313|EMBL:ABK75483.1};
DE            EC=1.2.99.2 {ECO:0000313|EMBL:ABK75483.1};
GN   OrderedLocusNames=MSMEG_0744 {ECO:0000313|EMBL:ABK75483.1};
OS   Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS   smegmatis).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=246196 {ECO:0000313|EMBL:ABK75483.1, ECO:0000313|Proteomes:UP000000757};
RN   [1] {ECO:0000313|EMBL:ABK75483.1, ECO:0000313|Proteomes:UP000000757}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000000757};
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000480; ABK75483.1; -; Genomic_DNA.
DR   RefSeq; WP_003892164.1; NZ_SIJM01000036.1.
DR   RefSeq; YP_885150.1; NC_008596.1.
DR   AlphaFoldDB; A0QQG2; -.
DR   STRING; 246196.MSMEG_0744; -.
DR   PaxDb; 246196-MSMEI_0728; -.
DR   GeneID; 66738919; -.
DR   KEGG; msm:MSMEG_0744; -.
DR   PATRIC; fig|246196.19.peg.740; -.
DR   eggNOG; COG1319; Bacteria.
DR   OrthoDB; 9793944at2; -.
DR   Proteomes; UP000000757; Chromosome.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.30.390.50; CO dehydrogenase flavoprotein, C-terminal domain; 1.
DR   Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR   InterPro; IPR005107; CO_DH_flav_C.
DR   InterPro; IPR036683; CO_DH_flav_C_dom_sf.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR002346; Mopterin_DH_FAD-bd.
DR   PANTHER; PTHR42659; XANTHINE DEHYDROGENASE SUBUNIT C-RELATED; 1.
DR   PANTHER; PTHR42659:SF2; XANTHINE DEHYDROGENASE SUBUNIT C-RELATED; 1.
DR   Pfam; PF03450; CO_deh_flav_C; 1.
DR   Pfam; PF00941; FAD_binding_5; 1.
DR   SMART; SM01092; CO_deh_flav_C; 1.
DR   SUPFAM; SSF55447; CO dehydrogenase flavoprotein C-terminal domain-like; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000313|EMBL:ABK75483.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000757}.
FT   DOMAIN          2..179
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
SQ   SEQUENCE   296 AA;  31673 MW;  36C68E11BD7D72C7 CRC64;
     MQVPGPFEYE RATSVDHAVG LLDRLGEDAR IVAGGHSLLP MMKLRIANPE YLVDINDLAV
     ELGYVITDPT LVRIGAMARH RQVLESDPLA AVCPIFRDAE RVIADPVVRN RGTLGGSLCQ
     ADPAEDLTTV CTILGAVCLA RGPGGEREIG IDDFLVGPYE TALAHNEMLV EVRIPVRHRT
     SSAYAKVERR VGDWAVTAAG AQVTLDGDSI VAARVGLTAV NPDPDALRAL ADDLIGKPAT
     EETFAAAGEL AVQACEPVTD TRGSADYKRH LARELTIRTM RTAVERVRTA PAPEGN
//