ID   K1QZ00_CRAGI            Unreviewed;       482 AA.
AC   K1QZ00;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Cytochrome P450 2C14 {ECO:0000313|EMBL:EKC26766.1};
GN   ORFNames=CGI_10028306 {ECO:0000313|EMBL:EKC26766.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC26766.1};
RN   [1] {ECO:0000313|EMBL:EKC26766.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC26766.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR   EMBL; JH816901; EKC26766.1; -; Genomic_DNA.
DR   RefSeq; XP_011435299.1; XM_011436997.2.
DR   AlphaFoldDB; K1QZ00; -.
DR   GeneID; 105333814; -.
DR   KEGG; crg:105333814; -.
DR   HOGENOM; CLU_001570_22_3_1; -.
DR   InParanoid; K1QZ00; -.
DR   OMA; ARYWGED; -.
DR   OrthoDB; 2952924at2759; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR008069; Cyt_P450_E_grp-I_CYP2D-like.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR24300:SF281; CYTOCHROME P450 2U1; 1.
DR   PANTHER; PTHR24300; CYTOCHROME P450 508A4-RELATED; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR01686; EP450ICYP2D.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW   Metal-binding {ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000461}.
SQ   SEQUENCE   482 AA;  55180 MW;  F09F271CD858CEA6 CRC64;
     MWVTVAIVVL LIALILRYTG RPKGLPPGPT CYPIIGNVGL VKPSEAVQAH RNLRKKYGDI
     YTIMTFHKPM IAVHGYDNIR ELLVKHGDTF SDRPLTIING VFNKGKGLVW SSGPLWKEQR
     TFALTTMRKF GFGKRCLQDQ IMEEVDCFME ELEKYENKPF DIQNILNTSV SNVICSLLFG
     KRFEYEDTKF KRLVVLLNKL FATGNASSPA FIFPVLRHLP MSRYTTVQNI FADIDGFTSE
     IIAEHRRNFD GNNINDFIDG FLLEQNEAGE NSTFTDEQLK ISVREFFAAG TETTSTTIRW
     SLLFLLHHPE WQQKLRDIID AGIGQSQPKM EHKEQLPLVE AFILEVQRHA NLVPLGLPHA
     PKEDFHYKGY HLPKGTFMFF ALDSVMTDPE IFPEPTKFKP ERFLDNDGKC NGEQKERLIP
     FSTGRRLCLG DSLAKMELFL FLTRLLQKFE IKPEKSECLP SLEGKLGITN MPAPFDIVLI
     KR
//