ID K1R737_CRAGI Unreviewed; 489 AA.
AC K1R737;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Cytochrome P450 2C8 {ECO:0000313|EMBL:EKC29816.1};
GN ORFNames=CGI_10007796 {ECO:0000313|EMBL:EKC29816.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC29816.1};
RN [1] {ECO:0000313|EMBL:EKC29816.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC29816.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; JH817999; EKC29816.1; -; Genomic_DNA.
DR RefSeq; XP_011449922.1; XM_011451620.2.
DR AlphaFoldDB; K1R737; -.
DR GeneID; 105344043; -.
DR KEGG; crg:105344043; -.
DR HOGENOM; CLU_001570_22_3_1; -.
DR InParanoid; K1R737; -.
DR OMA; LAMPRKF; -.
DR OrthoDB; 2953911at2759; -.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24300:SF385; CYTOCHROME P450 306A1; 1.
DR PANTHER; PTHR24300; CYTOCHROME P450 508A4-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461}.
SQ SEQUENCE 489 AA; 56145 MW; 09844D394A76F901 CRC64;
MFDFWTIFLA VVVGILYIWW KNTTRDAVLP PGPPTVPFLG NLLSVNPETV LDTFQEYRRK
YGEVFSLITG SKTLVVISGY DTLREIFIKH GDVTSERPDI FITREVGKFK GVATSSGALW
KEHRTFSLNT LREFGFGKRS LESRIIEEIE VFVHEIQSKK GEPFNIHSLI NVCISNIMCS
ITFGKRYDHD DKKFLSLLNS INQNLSNENV MFVATVLPFI RYIPGDPFRI KKVLRNVDKV
ENHLRQLVEE HEQIYDENNL RDYVDVFLKK MKSERNNPNT TFDEDQLLKI VGELFVAGTE
TTSTAIRWFC LFMIRHPEVQ EKMRNEINDV IGTSRFPSLE DKQNLPYCEA VIHETLRIGT
IAPLSVPHGL ASDLKFNGFT IPKDALLIPN LYSVFFDENI FPDPYDFKPE RFLDEKGNLK
NTDKVLAFSL GRRVCLGEAL ARMELFLFVT SLIQRFTLEA GDIRNIPSEK GTMGITYAPK
DFVLKAVPT
//
