ID   K1X3W7_MARBU            Unreviewed;      1193 AA.
AC   K1X3W7;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   ORFNames=MBM_06624 {ECO:0000313|EMBL:EKD15408.1};
OS   Marssonina brunnea f. sp. multigermtubi (strain MB_m1) (Marssonina leaf
OS   spot fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Drepanopezizaceae; Drepanopeziza.
OX   NCBI_TaxID=1072389 {ECO:0000313|EMBL:EKD15408.1, ECO:0000313|Proteomes:UP000006753};
RN   [1] {ECO:0000313|EMBL:EKD15408.1, ECO:0000313|Proteomes:UP000006753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MB_m1 {ECO:0000313|EMBL:EKD15408.1,
RC   ECO:0000313|Proteomes:UP000006753};
RX   PubMed=22876864; DOI=10.1186/1471-2164-13-382;
RA   Zhu S., Cao Y.-Z., Jiang C., Tan B.-Y., Wang Z., Feng S., Zhang L.,
RA   Su X.-H., Brejova B., Vinar T., Xu M., Wang M.-X., Zhang S.-G.,
RA   Huang M.-R., Wu R., Zhou Y.;
RT   "Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-
RT   evolution.";
RL   BMC Genomics 13:382-382(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
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DR   EMBL; JH921442; EKD15408.1; -; Genomic_DNA.
DR   RefSeq; XP_007294513.1; XM_007294451.1.
DR   AlphaFoldDB; K1X3W7; -.
DR   GeneID; 18762559; -.
DR   KEGG; mbe:MBM_06624; -.
DR   eggNOG; KOG0988; Eukaryota.
DR   HOGENOM; CLU_001366_2_0_1; -.
DR   InParanoid; K1X3W7; -.
DR   OMA; VDEKKIW; -.
DR   OrthoDB; 5477883at2759; -.
DR   Proteomes; UP000006753; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF17; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   Pfam; PF05183; RdRP; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006753};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
SQ   SEQUENCE   1193 AA;  135552 MW;  2BC660ABF381BA4C CRC64;
     MEIFIRDVPG QVTENGMRRQ LQPYIDKLSI KTYHCRKQIQ KRFATVTFLH VQEGQSFLKA
     YGGQFKAPNF SGEQQQLRIL GTPVYCTISA KKVNQLLLKS LAKEEKDRLT LDEKPATKAR
     TISGTTRSFS FSSVSCGVWG YEGSKLCFIP YFSHNHHGEG VAKFGTRSVV LTLESGERLD
     FLYASTKSIT TENVPKPSIT FTLWEAPRIY QSTSNDPIPQ LVAKMGQMSF GAPKSNQRSR
     VSALGKAHVQ TVISCFVYRI ALTAEPEELR KPLLNLQRAP GIPPIIHQQV EVHPPETSFS
     VQLKRLDEIL SDTRNIPWIL AFQLRGLVMN GVLTPEQTRQ LIPEVLAIMR RNGVTIAVAA
     VRKLGTQIPF PGLETQAYQF DTARFQMQLQ FNADRAKKEE LKALVDGSIS KSENHAMIHR
     VTITPSGFYL GGPEYEPMNR VLRQYPKHHD SFIRVSFADE DGEPIRFNPK VSNEKIFQDR
     FGTFLSTGFH VAGRKFDFLG FSHSSLRAQS CWFMSPFAHN GSLMYDRVLI QQLGDFTKIR
     CPAKCAARIG QAFSETPIAV PLEPGLVQLL PDVERGSRVF SDGCGKISRS IMHRIWAVLP
     DMRKHQPTCF QIRYQGAKGM LSLDDTLEGD QVLMRPSMIK FDGSPSFDLE LCNASYKSLP
     MYLNRQLIKI MEDIGVPDQW FLDLQSQEIE RLRKATTSAS NAAKFLSSHS IGDRVHLSWL
     IRKLAQMSIE FRTDRFLCDV LELSVMLEVK TLKHRARYPV PEGLTLYGIM DETGILEEGE
     IYCTYQSQKG KRMVVIQDRV LVTRSPALHP GDVQPVKAVN VPRDSPLSKL RNCICFSQKG
     DRDLPSMLSG GDLDGDLYNI IWDPGCQIRF KSFPADYPRQ DPIDIGRQVS REDMTKFFVQ
     FMETDQLGRI AMSHQILADQ KDMGTFDEDC RILAEMHSTA VDFSKTGVPV DMKKMPKFTP
     IRPDFMSMGN HVRMEKKEGL LLEATTLSTQ DDNNDDDDFP AYRYYESDRI LGKLYRAIDE
     HEVFSEIKKY RMLSRKTPSV LDRVWVHVHK KCWNLQWAQH VLWAQEIREM YEDNLRNIMS
     SYSEHPSRPI SELEAFIGNI LSVTGTQSKK QRDLSVTMKE AFDRDAGFVV DCIIYDEEGE
     YAENALEKSM ACLSVCLGQG SAFVRAGRDS EVLVSFGYLA AAVCLREMEC YFT
//