ID K6Z4H3_9ALTE Unreviewed; 873 AA.
AC K6Z4H3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00022419, ECO:0000256|HAMAP-Rule:MF_00595};
DE Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305, ECO:0000256|HAMAP-Rule:MF_00595};
GN Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN ORFNames=C427_4843 {ECO:0000313|EMBL:AGH46942.1};
OS Paraglaciecola psychrophila 170.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Paraglaciecola.
OX NCBI_TaxID=1129794 {ECO:0000313|EMBL:AGH46942.1, ECO:0000313|Proteomes:UP000011864};
RN [1] {ECO:0000313|EMBL:AGH46942.1, ECO:0000313|Proteomes:UP000011864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=170 {ECO:0000313|EMBL:AGH46942.1,
RC ECO:0000313|Proteomes:UP000011864};
RX PubMed=23640379;
RA Yin J., Chen J., Liu G., Yu Y., Song L., Wang X., Qu X.;
RT "Complete Genome Sequence of Glaciecola psychrophila Strain 170T.";
RL Genome Announc. 1:E00199-13(2013).
CC -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC for the tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003670,
CC ECO:0000256|HAMAP-Rule:MF_00595}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC Evidence={ECO:0000256|ARBA:ARBA00001071, ECO:0000256|HAMAP-
CC Rule:MF_00595};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946,
CC ECO:0000256|HAMAP-Rule:MF_00595};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC {ECO:0000256|ARBA:ARBA00008346, ECO:0000256|HAMAP-Rule:MF_00595}.
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DR EMBL; CP003837; AGH46942.1; -; Genomic_DNA.
DR RefSeq; WP_007642619.1; NZ_BAES01000088.1.
DR AlphaFoldDB; K6Z4H3; -.
DR STRING; 1129794.C427_4843; -.
DR KEGG; gps:C427_4843; -.
DR PATRIC; fig|1129794.4.peg.4825; -.
DR eggNOG; COG2352; Bacteria.
DR HOGENOM; CLU_006557_2_0_6; -.
DR OrthoDB; 9768133at2; -.
DR Proteomes; UP000011864; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR HAMAP; MF_00595; PEPcase_type1; 1.
DR InterPro; IPR021135; PEP_COase.
DR InterPro; IPR022805; PEP_COase_bac/pln-type.
DR InterPro; IPR018129; PEP_COase_Lys_AS.
DR InterPro; IPR033129; PEPCASE_His_AS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR30523:SF6; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR Pfam; PF00311; PEPcase; 1.
DR PRINTS; PR00150; PEPCARBXLASE.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR PROSITE; PS00781; PEPCASE_1; 1.
DR PROSITE; PS00393; PEPCASE_2; 1.
PE 3: Inferred from homology;
KW Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300, ECO:0000256|HAMAP-
KW Rule:MF_00595};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00595};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|HAMAP-Rule:MF_00595};
KW Pyruvate {ECO:0000313|EMBL:AGH46942.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011864}.
FT ACT_SITE 133
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT ECO:0000256|PROSITE-ProRule:PRU10111"
FT ACT_SITE 538
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT ECO:0000256|PROSITE-ProRule:PRU10112"
SQ SEQUENCE 873 AA; 98145 MW; ED2ED0DAC76544D3 CRC64;
MTQALDSQLV GTVRNLGAVL GDTIRDQLGE QWLERIEAVR KDGRKAHQGD EESAKRVKQL
FTELKNDELL TVGRAFSQFL NLANIAEQEF NSNNDQVDPM DTLFSHLDQA DIKADTFEKA
LQHLNIELVL TAHPTEVTRR TLIHKHSELA KCLSKVHVSD INEVERDKIE TRIAELISQA
WHTEEIRTIR PTPVDEARWG FSVIENSLWE AVPDFIRELD KRFVDKFGLS IPLDVSPVKF
GSWMGGDRDG NPFVTSKVTE QVLLLARKRA AKLFAKDIDI LQTELSMSDC DDDLRAKVGD
ELEPYRAILR PLLEKLVKTQ TGIVEKLKGI PVDMTDWVDN KEQLLVPLMT CYHSLQACGM
SVIAQGHLQN TIRRIHCFGV HLLKLDVRQD SERHADVFSE LTRYLGLGDY GQWSEDDKQA
FLLKELGSKR PLFPPAWQPS EDVQEVLDTC KVIAQNGKDG FGIYIISMAS LPSDVLSVNL
LLKELGVTWP MPVAPLFETL DDLNAAASVT KKLFSIDWYR GYIQAHQYVM IGYSDSAKDA
GAMAAGWAQY ESQEALVALA EENDIELTLF HGRGGTIGRG GLPAHAAILS QPPGSLTGGF
RVTEQGETIR YKFGMPILAQ RSLALYASAI LEALILPPPA PKQAWREAMI KMAADGRDNY
RQIVRHDENF VPYFRVATPE QELGKLPLGS RPAKRKPTGG IESLRAIPWI FAWAQTRMVL
PSWLGVMKSV QSSLDAGKED TIQDMLANWP FFYSRLSMLD MVFAKADPKI SQEYDKSLVP
KELRHFGDAL RTELQQSIDL LLKLLDQKTV MESDPKGSVS MNIRASYLQP LHYLQIELLK
RIRQLDDKEH DATLERAMMV TIAGIAVGMR NTG
//
