ID Q2UL81_ASPOR Unreviewed; 625 AA.
AC Q2UL81;
DT 24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT 24-JAN-2006, sequence version 1.
DT 13-SEP-2023, entry version 78.
DE RecName: Full=Phospholipid:diacylglycerol acyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AO090003000514 {ECO:0000313|EMBL:BAE57684.1};
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516 {ECO:0000313|EMBL:BAE57684.1, ECO:0000313|Proteomes:UP000006564};
RN [1] {ECO:0000313|EMBL:BAE57684.1, ECO:0000313|Proteomes:UP000006564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40 {ECO:0000313|Proteomes:UP000006564};
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
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DR EMBL; AP007155; BAE57684.1; -; Genomic_DNA.
DR RefSeq; XP_001819686.1; XM_001819634.1.
DR AlphaFoldDB; Q2UL81; -.
DR STRING; 510516.Q2UL81; -.
DR ESTHER; aspor-q2ul81; PC-sterol_acyltransferase.
DR EnsemblFungi; BAE57684; BAE57684; AO090003000514.
DR GeneID; 5991669; -.
DR KEGG; aor:AO090003000514; -.
DR VEuPathDB; FungiDB:AO090003000514; -.
DR HOGENOM; CLU_016065_1_0_1; -.
DR OMA; SMGSQVI; -.
DR OrthoDB; 589269at2759; -.
DR Proteomes; UP000006564; Chromosome 2.
DR GO; GO:0032541; C:cortical endoplasmic reticulum; IEA:EnsemblFungi.
DR GO; GO:0005811; C:lipid droplet; IEA:EnsemblFungi.
DR GO; GO:0005637; C:nuclear inner membrane; IEA:EnsemblFungi.
DR GO; GO:0097038; C:perinuclear endoplasmic reticulum; IEA:EnsemblFungi.
DR GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR GO; GO:0046027; F:phospholipid:diacylglycerol acyltransferase activity; IEA:EnsemblFungi.
DR GO; GO:0006672; P:ceramide metabolic process; IEA:EnsemblFungi.
DR GO; GO:0140042; P:lipid droplet formation; IEA:EnsemblFungi.
DR GO; GO:0055091; P:phospholipid homeostasis; IEA:EnsemblFungi.
DR GO; GO:0019432; P:triglyceride biosynthetic process; IEA:EnsemblFungi.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR003386; LACT/PDAT_acylTrfase.
DR PANTHER; PTHR11440:SF97; BCDNA.GH02384; 1.
DR PANTHER; PTHR11440; LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED; 1.
DR Pfam; PF02450; LCAT; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006564};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 55..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 625 AA; 69875 MW; B11473D12EE4D110 CRC64;
MLRRRLAKDD NVQSASTDSS RDESKVVPAT QTATPAEKPK KESFVTKPRS KRRNGLIFVL
GGIFGIIVAA FFANQQDVIS LDALMDLNLD ALMDVIPQGI VKDVREFSQH ERDAVSYDSF
SVGLQLQSQG IQAKHPIVMI PGVISTGLES WGTEVSSRQY FRRRLWGSWS MMRALVLDKA
EWKNHIMLDK DTGLDPPGIK LRAAQGFDAT DFFITGYWIW NKILENLATI GYDPTNAFTA
AYDWRLSYLN LEVRDQYFSR LKSYIETAVL VKGEKVALAS HSMGSQVLFY FFKWVEHPEH
GKGGSDWVNR HVASWINISG CMLGAVKGLT AVLSGEMRDT AQLNAFAVYG LEKFLSKEER
AEIFRAMPGI SSMLPKGGEA VWGNATWAPD DLPGQHTSYG NLLKFQQTNS SLTAKNLTVS
ESLAYLMNSS DEWYRNQVQT SYSHGVAHTT AQVEANENDP RTWLNPLEAR LPLAPDMKVY
CFYGVGKPTE RSYYYQEERD PLVNLNVSID TTVTNSDGVD HGVVMGEGDG TVNLLSTGYM
CAKGWNIKRY NPAGVKIKVF EMPHEPDRFS PRGGPNTGDH VDILGRASLN ELILRVAGGH
GDEIEETFVS KIKEYADRVQ IFEEE
//
