ID Q4KJH8_PSEF5 Unreviewed; 408 AA.
AC Q4KJH8;
DT 02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT 02-AUG-2005, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Putative 3-oxoacyl-[acyl-carrier-protein] synthase {ECO:0000313|EMBL:AAY95870.1};
DE EC=2.3.1.41 {ECO:0000313|EMBL:AAY95870.1};
GN OrderedLocusNames=PFL_0461 {ECO:0000313|EMBL:AAY95870.1};
OS Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=220664 {ECO:0000313|EMBL:AAY95870.1, ECO:0000313|Proteomes:UP000008540};
RN [1] {ECO:0000313|EMBL:AAY95870.1, ECO:0000313|Proteomes:UP000008540}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-477 / NRRL B-23932 / Pf-5
RC {ECO:0000313|Proteomes:UP000008540};
RX PubMed=15980861; DOI=10.1038/nbt1110;
RA Paulsen I.T., Press C.M., Ravel J., Kobayashi D.Y., Myers G.S.,
RA Mavrodi D.V., DeBoy R.T., Seshadri R., Ren Q., Madupu R., Dodson R.J.,
RA Durkin A.S., Brinkac L.M., Daugherty S.C., Sullivan S.A., Rosovitz M.J.,
RA Gwinn M.L., Zhou L., Schneider D.J., Cartinhour S.W., Nelson W.C.,
RA Weidman J., Watkins K., Tran K., Khouri H., Pierson E.A., Pierson L.S.III.,
RA Thomashow L.S., Loper J.E.;
RT "Complete genome sequence of the plant commensal Pseudomonas fluorescens
RT Pf-5.";
RL Nat. Biotechnol. 23:873-878(2005).
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
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DR EMBL; CP000076; AAY95870.1; -; Genomic_DNA.
DR RefSeq; WP_011058835.1; NC_004129.6.
DR AlphaFoldDB; Q4KJH8; -.
DR STRING; 220664.PFL_0461; -.
DR GeneID; 57473450; -.
DR KEGG; pfl:PFL_0461; -.
DR PATRIC; fig|220664.5.peg.473; -.
DR eggNOG; COG0304; Bacteria.
DR HOGENOM; CLU_000022_69_2_6; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000008540; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF325; 3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE II FABF; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:AAY95870.1};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:AAY95870.1}.
FT DOMAIN 1..406
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 408 AA; 43747 MW; 0924F637D3EE423B CRC64;
MKRVVVTGMA GITSLGSDWA SIAERFAANR SGIRRMDEWD RFSELNTRLA GPIDDFQVPG
HWTRKQLRSM GRVSRLAVGA AEQALADAGL LGDPSIKDGR MGVACGSSTG STDEIKAFGN
MLLNSVAEGL NANSYVRMMP HTTAANISIF FGLTGRLIPT SSACTSGSQG IGYAYEAIKF
GRLPLMLAGG AEELCPTEAM VFDALYATSL KNDAPHTSPR PYDSGRDGLV IGEGGGMLVL
EELEHALARG ARIHAEIVGF GSNADGQHTT RPEQSTMRRA MELALEDGAL APEAIGYVNG
HGTATEQGDI AETLATSSLF GSRMPISSQK SFLGHTLGAC GALESWFSIE MLNRDLYVHT
CNLDQVDPRC GELDYLQGGF RAMSHEYVMN NNFAFGGVNT SLIFRRWS
//
