ID Q54SZ7_DICDI Unreviewed; 2562 AA.
AC Q54SZ7;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=HECT domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DDB_G0282111 {ECO:0000313|EMBL:EAL66381.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL66381.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL66381.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL66381.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL66381.1}.
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DR EMBL; AAFI02000045; EAL66381.1; -; Genomic_DNA.
DR RefSeq; XP_640358.1; XM_635266.1.
DR AlphaFoldDB; Q54SZ7; -.
DR GeneID; 8623413; -.
DR KEGG; ddi:DDB_G0282111; -.
DR dictyBase; DDB_G0282111; -.
DR HOGENOM; CLU_228103_0_0_1; -.
DR InParanoid; Q54SZ7; -.
DR OMA; GCASERI; -.
DR Proteomes; UP000002195; Chromosome 3.
DR PANTHER; PTHR32488:SF77; LISH DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR32488; UPF0746 PROTEIN DDB_G0280785-RELATED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002195}.
FT REGION 111..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1496..1545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1902..1925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..433
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..475
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1510..1530
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1910..1925
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2562 AA; 298724 MW; C5AAB592AF21F1E9 CRC64;
MTIAVANRAS SVKTLGTSSL AIKHEYDSRN KSSLNFFSDQ TTLEDGNTSF DEKVLYIKRV
LINDFRSKNH IVDMGKAIGI DVPPKDTKAN VLTLMIAFVN DYLDQKKKRL ESNSSWDPNG
GNYIDHNEFF KTPTPGQRQV YNDDINDDNG NNNNNNSNNN INTNNNININ TNINTNTNNN
TNNNTNINTN ANTNTNTYSN TNINNNTNTN SNGFNGNNID NGSLNNNNFN NNSNNIDNGS
LNNSNNIDNC SLNNNSNNNN NSNSNSNSNN NNNNNNYYNN NNNNNNNYNN YNGSYNCNNN
NNSYYYNNNS SNNNNNSYNN NNNYYNSNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNR
YDCNNNNNYS NNNSNSNSNN NSNYSNNSYD CNNDNNNNIF SNSNGHNDND IGNDFDNDND
NDSYIDDDNN VYDNNDGDYN NNKNNNYNNN NNNNNNNNNS NNNNNNNNNN RSNYYGNEDN
NINCIDTNGN GNGNIYSCSN SNSNSYSNSN SNSNSNSNSN SNNNSNNSNN SNNSNSNSNN
NINNNNINNN NTNNNNNNNS YICNNNNNNN NNNNNKNNNN NNNNNNNNNN NNNSLYGKDN
EGFSNQINDN FNFYKSQGNN ILEDFNLNNF QTNDKILKEM IDKLNNYGIS IKPKIGKGNS
QMIVNEGERE NKERLFWSVF RDKSLLDKIV SYLAECIQGK PKLTSFKYYN IVHIKWMLDN
DYIELIQDKV FRNETLLFGA YKSEDMTKEE VVSILFKKVN QKNCKNSEEI EKQLKFYQLL
VHRFGNEIFK GINGGIQGLL ELAITAKNSI ALIVLFSMIE SNYTLTDEIL LNSFKCTIKV
NSFSMIKLIT FKIIKKDYQI IRNYQEVTNT TFEQIFQSII NPSIKIINFL IDIGIVMFSF
KRDDSPPICF DSILVKSNSN TLASEISTRK KNLRFVKEYK TIIGESGFIN SNCGVISIEM
DKHEPHPSRP SIFNKNSLKE IINACYLNIN FNYDKNSPLL KRQIETLFLF YPVFYSTVEV
ISIITNRIEA VRNCFSKEQL SLKLKHLIKI YPEDSIQFKG INCLVSFYLS FDFQSKFYCL
YLHYLIFGNF ISNINSDVLN VLPKDFDLNY FEKSLKYGSS IYCAKFKNEI ARNFPKLVKD
KKFFILFKHC DKNSVASRYK KLEFFRTIIN QQSHSTERCN FALFCLLIST NDLELIEAAC
NEFTVFKEGF SYDFRDKQSN LYKYCNQMYF KVKITIIDFI KTVEVSHFTL QNYLYLFKDF
EKDFQVKHFK SSEVFIHYCQ TFLSNYRGNN GQLVFIDTHV GDNMDLKSYN SFWNIVAFLI
RNPLNINFKI IDPYTLFFNI TLKISNINVD NNNNSAVMNS NQRDYEIFNN IFENIKYVIT
NYQPNGYIVY YKPSSLFGGD LYWCNKLIDW IFDNAKDDII NKRCKIEESD LIKCGKFNYL
FYERGYYYFD SIRNRYLPFS GHPILDSGRL GNINLLHLFL NTSGLQIFEK EANREDRVRK
QKGKKDKESS SSGSSIGNPS SSGGSDFYNL DDSENESDSE NNNEIEDDMK SIYRFKEDFT
SILMNASRYG RLNIFQYLYF NYPFLVSKRS WIAADNLVSK ATRFGLLQNT TFQNIGKTAE
DNEKERQNDT RKKSYCNLPI KVKEKVEKLF WRVFKDKYLF REIFSKISNC RPSNEIYGIS
IFKYKDIIHF SWMIEFGYFE LLKYKIKRNE LILFSDHRSN GEIVMKREEN FKIKYFKFLF
KFFNGSSKEN HNEIILFYQQ LFKNYYKQIE KEFKISELIN ESINEKCIEP LIVLIEQLKI
TGFGLDDSLL AIAKTRSLKF TKLIVSQVKN FRNSDDFGLE QPLTNYLLEN LYNPPLKIIN
YLLESNIITL ENVKLLVNSG ISNLILNNNF EITLDKPNYK KRKKIDDDHD DDNDDDEEED
EEDIYTSDTE INRNTIFLKS LLKNSKFLKE DLKSKGLKSI FNYSLKELIN SCSIIITFDL
KQRNKHRHQH QHQHHQNKDQ QPIFKTSKSL INTMEEIENI KKKFSKELLN TKIKLIYKNN
GQELSNDIKL LLELYLSIDS YSKRYCNFMF HYIYTYQNQD NICISKNNFL NQVYLKKSLI
YGSSYYWVKN INITSKYILN IIKLKNGNLN LLFKHCPHDS KKQIDFIKQI YNNCSNQNRF
LLFYLLIDFD DLNLIKFVDK NYSDLSKIIV EYSVFNDLKI QRFIKSERML RYCVSNHFDH
FDYIYTSNIP TQVCDFFGFC NTELLELHDR LVLAAIHRKK QRYQINDSSL IEQQHTDDDD
NNNNNSVMIM KNVTISSPMK FINSIVGFGV DFKTFYDYIK MLRYVVENIH KNYNVIQDES
VLRMVALSGD CTNKQFKMVF TDIKFIINNT KVSYYPYDLF KKPSQLKQFF DWIFLERPQD
LQGIVKRCQC VPVVLYKAGN IINLLEKGSD NFYQESPDDL LPNSNSFKKV SKEIGRLGDV
VSLEFFLQLI GIPIIGKSKE PSTDLHDFNM LKENLIEILK KASSFGRINI FQHLYNNHQN
LLLKKSNSMA GFLSNLDYQI ILNNAKDNHN NHIFEFIKNL IG
//
