ID Q60BN0_METCA Unreviewed; 403 AA.
AC Q60BN0;
DT 23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT 23-NOV-2004, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=MotA/TolQ/ExbB proton channel family protein {ECO:0000313|EMBL:AAU90389.1};
GN OrderedLocusNames=MCA0436 {ECO:0000313|EMBL:AAU90389.1};
OS Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylococcus.
OX NCBI_TaxID=243233 {ECO:0000313|EMBL:AAU90389.1, ECO:0000313|Proteomes:UP000006821};
RN [1] {ECO:0000313|EMBL:AAU90389.1, ECO:0000313|Proteomes:UP000006821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33009 / NCIMB 11132 / Bath
RC {ECO:0000313|Proteomes:UP000006821};
RX PubMed=15383840; DOI=10.1371/journal.pbio.0020303;
RA Ward N.L., Larsen O., Sakwa J., Bruseth L., Khouri H.M., Durkin A.S.,
RA Dimitrov G., Jiang L., Scanlan D., Kang K.H., Lewis M.R., Nelson K.E.,
RA Methe B.A., Wu M., Heidelberg J.F., Paulsen I.T., Fouts D.E., Ravel J.,
RA Tettelin H., Ren Q., Read T.D., DeBoy R.T., Seshadri R., Salzberg S.L.,
RA Jensen H.B., Birkeland N.K., Nelson W.C., Dodson R.J., Grindhaug S.H.,
RA Holt I.E., Eidhammer I., Jonasen I., Vanaken S., Utterback T.R.,
RA Feldblyum T.V., Fraser C.M., Lillehaug J.R., Eisen J.A.;
RT "Genomic insights into methanotrophy: the complete genome sequence of
RT Methylococcus capsulatus (Bath).";
RL PLoS Biol. 2:1616-1628(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU004057}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004057}.
CC -!- SIMILARITY: Belongs to the exbB/tolQ family.
CC {ECO:0000256|RuleBase:RU004057}.
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DR EMBL; AE017282; AAU90389.1; -; Genomic_DNA.
DR RefSeq; WP_010959795.1; NC_002977.6.
DR AlphaFoldDB; Q60BN0; -.
DR STRING; 243233.MCA0436; -.
DR KEGG; mca:MCA0436; -.
DR eggNOG; COG0811; Bacteria.
DR HOGENOM; CLU_047225_1_0_6; -.
DR Proteomes; UP000006821; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR002898; MotA_ExbB_proton_chnl.
DR PANTHER; PTHR30625; PROTEIN TOLQ; 1.
DR PANTHER; PTHR30625:SF11; TOLQ-TYPE TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF01618; MotA_ExbB; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|RuleBase:RU004057};
KW Reference proteome {ECO:0000313|Proteomes:UP000006821};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU004057}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..403
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004266511"
FT TRANSMEM 211..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 255..370
FT /note="MotA/TolQ/ExbB proton channel"
FT /evidence="ECO:0000259|Pfam:PF01618"
SQ SEQUENCE 403 AA; 42347 MW; 578D85E707A083A2 CRC64;
MKGLSLFRNL AGAAAGLVFF ATARPGFPAP PPEPSGLGAA PTAALDALFL AVRESAANLK
LFYEQNYLAG DGPGQRRLLD RLADPQHVPA AAELEDLFAS LGAQMDALGR VSTFRAPVYA
PDGRMAEREV LRLGGFGFIA GRRYLVYAPE VRALAELARQ PSSALLDLAQ RFAQVDADSL
APVALDPSGG QTLQLLVQVP DLAERIAQGG AVGYLILALA TFALVLGGCR FADLARTSRR
IRRQLGSLEA RSDNPLGRVL LRLEQAQTED EDALYLTVDE ALAGERMRLE RALGLLKLVA
AIAPMLGLLG TVTGMIRTFQ AIALHGSGDP RLMSGGISEA LVTTVEGLVT AIPILLLHSV
LVGKAQALGT LLEAQASAAL SARLAGRRDR TVAVAGGPRL LEG
//
