ID Q825P2_STRAW Unreviewed; 386 AA.
AC Q825P2;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Sugar isomerase {ECO:0000313|EMBL:BAC75126.1};
GN ORFNames=SAVERM_7415 {ECO:0000313|EMBL:BAC75126.1};
OS Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC75126.1, ECO:0000313|Proteomes:UP000000428};
RN [1] {ECO:0000313|EMBL:BAC75126.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=11572948; DOI=10.1073/pnas.211433198;
RA Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M.;
RT "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT deducing the ability of producing secondary metabolites.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN [2] {ECO:0000313|EMBL:BAC75126.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=12692562; DOI=10.1038/nbt820;
RA Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M., Omura S.;
RT "Complete genome sequence and comparative analysis of the industrial
RT microorganism Streptomyces avermitilis.";
RL Nat. Biotechnol. 21:526-531(2003).
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DR EMBL; BA000030; BAC75126.1; -; Genomic_DNA.
DR RefSeq; WP_010988810.1; NZ_JZJK01000065.1.
DR AlphaFoldDB; Q825P2; -.
DR KEGG; sma:SAVERM_7415; -.
DR eggNOG; COG4952; Bacteria.
DR HOGENOM; CLU_059875_0_0_11; -.
DR OrthoDB; 5174871at2; -.
DR Proteomes; UP000000428; Chromosome.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.150; Divalent-metal-dependent TIM barrel enzymes; 1.
DR InterPro; IPR013457; Rhamnose_iso-rel.
DR InterPro; IPR036237; Xyl_isomerase-like_sf.
DR InterPro; IPR013022; Xyl_isomerase-like_TIM-brl.
DR NCBIfam; TIGR02635; RhaI_grampos; 1.
DR PANTHER; PTHR30268; L-RHAMNOSE ISOMERASE; 1.
DR PANTHER; PTHR30268:SF0; L-RHAMNOSE ISOMERASE; 1.
DR Pfam; PF01261; AP_endonuc_2; 1.
DR SUPFAM; SSF51658; Xylose isomerase-like; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:BAC75126.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT DOMAIN 71..245
FT /note="Xylose isomerase-like TIM barrel"
FT /evidence="ECO:0000259|Pfam:PF01261"
SQ SEQUENCE 386 AA; 42624 MW; 9A88ED7BA7FDAADF CRC64;
MTELAAVKAA LKTQAVETPS WAYGNSGTRF KVFAQPGVPR TPQEKLDDAA QVHAYTGAAP
TVALHIPWDR VEDYAKLAEY AEERGLKLGT INSNTFQDDA YKLGSICHPE AAVRRKALDH
LLECVDIMDA TGSKDLKLWF ADGTNYPGQD DVRERQDRLT EGLATVYERL GDDQRMLLEY
KFFEPAFYTT DVPDWGTAYA HCLKLGDRAQ VVVDTGHHAP GTNIEFIVAT LLREGKLGGF
DFNSRFYADD DLMVGAADPF QLFRIMYEVI RGGGLTSDVA FMLDQCHNIE AKIPAIIRSV
MNVQEATAKA LLVDREALRS AQRSGDVLEA NAVLMDAYNT DVRPLLAELR EETGLDPDPV
AAYRRSGWAS KIAEERVGGQ QAGWGA
//
