ID S4YLA2_SERPL Unreviewed; 478 AA.
AC S4YLA2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Catalase {ECO:0000256|ARBA:ARBA00014132, ECO:0000256|RuleBase:RU000498};
DE EC=1.11.1.6 {ECO:0000256|RuleBase:RU000498};
GN ORFNames=M621_17390 {ECO:0000313|EMBL:AGP45301.1};
OS Serratia plymuthica S13.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=1348660 {ECO:0000313|EMBL:AGP45301.1, ECO:0000313|Proteomes:UP000014900};
RN [1] {ECO:0000313|EMBL:AGP45301.1, ECO:0000313|Proteomes:UP000014900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S13 {ECO:0000313|EMBL:AGP45301.1};
RX PubMed=23929484;
RA Muller H., Furnkranz M., Grube M., Berg G.;
RT "Genome Sequence of Serratia plymuthica Strain S13, an Endophyte with
RT Germination- and Plant-Growth-Promoting Activity from the Flower of Styrian
RT Oil Pumpkin.";
RL Genome Announc. 1:e00594-13(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6;
CC Evidence={ECO:0000256|ARBA:ARBA00000720,
CC ECO:0000256|RuleBase:RU000498};
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971,
CC ECO:0000256|PIRSR:PIRSR038928-2};
CC -!- SIMILARITY: Belongs to the catalase family.
CC {ECO:0000256|ARBA:ARBA00005329, ECO:0000256|RuleBase:RU000498}.
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DR EMBL; CP006566; AGP45301.1; -; Genomic_DNA.
DR RefSeq; WP_004947182.1; NC_021659.1.
DR AlphaFoldDB; S4YLA2; -.
DR KEGG; sry:M621_17390; -.
DR PATRIC; fig|1348660.3.peg.3420; -.
DR eggNOG; COG0753; Bacteria.
DR HOGENOM; CLU_010645_2_0_6; -.
DR Proteomes; UP000014900; Chromosome.
DR GO; GO:0004096; F:catalase activity; IEA:UniProtKB-EC.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd08156; catalase_clade_3; 1.
DR Gene3D; 2.40.180.10; Catalase core domain; 1.
DR InterPro; IPR018028; Catalase.
DR InterPro; IPR040333; Catalase_3.
DR InterPro; IPR024708; Catalase_AS.
DR InterPro; IPR024711; Catalase_clade1/3.
DR InterPro; IPR011614; Catalase_core.
DR InterPro; IPR002226; Catalase_haem_BS.
DR InterPro; IPR010582; Catalase_immune_responsive.
DR InterPro; IPR020835; Catalase_sf.
DR PANTHER; PTHR11465; CATALASE; 1.
DR PANTHER; PTHR11465:SF61; CATALASE; 1.
DR Pfam; PF00199; Catalase; 1.
DR Pfam; PF06628; Catalase-rel; 1.
DR PIRSF; PIRSF038928; Catalase_clade1-3; 1.
DR PRINTS; PR00067; CATALASE.
DR SMART; SM01060; Catalase; 1.
DR SUPFAM; SSF56634; Heme-dependent catalase-like; 1.
DR PROSITE; PS00437; CATALASE_1; 1.
DR PROSITE; PS00438; CATALASE_2; 1.
DR PROSITE; PS51402; CATALASE_3; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR038928-2};
KW Hydrogen peroxide {ECO:0000256|ARBA:ARBA00023324,
KW ECO:0000256|RuleBase:RU000498};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR038928-2};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR038928-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000498};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559, ECO:0000256|RuleBase:RU000498}.
FT DOMAIN 7..391
FT /note="Catalase core"
FT /evidence="ECO:0000259|SMART:SM01060"
FT ACT_SITE 54
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT ACT_SITE 127
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT BINDING 337
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-2"
SQ SEQUENCE 478 AA; 54754 MW; 81E1161A88A2976B CRC64;
MSKKGLTTAA GAPVVDNNNV ITAGKRGPML LQDVWFLEKL AHFDREVIPE RRMHAKGSGA
YGTFTVTHDI TRYTRAKIFA EIGKQTDMFI RFSTVAGERG AADAERDIRG FAMKFYTDEG
NWDLVGNDTP VFYLRDPLKF PDLNHVVKRD PHTNLRNPVY KWDFFSHLPE SLHQLTIDFS
DRGIPKSYRH MHGFGSHTFS FINANNERFW VKFHFRCEQG IENLMDDEAE AIIAKDRESS
QRDLFDAIKR GDFPRWKLQI QIMPEHEASQ TPYNPFDLTK VWPHGDYPLI DVGFFELNRN
PDNYFSEVEQ VAMNPANVVP GVSFSPDKML QGRLFSYGDA HRYRLGVNHH QIPVNGAKCP
FHNYHRDGAM RVDGNSGNGA TYEPNSFGLF QEQPDFSEPP LSIEGAADHW NHREDKDYFS
QPRALFNLLS AEEHQRMFTR IAGELSQVPE QIQRRQVDLF TQVHPDYGAG VASALGLK
//
