ID U5Q741_9BACT Unreviewed; 453 AA.
AC U5Q741;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN Name=ywdH {ECO:0000313|EMBL:AGY54336.1};
GN ORFNames=BRDCF_p1709 {ECO:0000313|EMBL:AGY54336.1};
OS Bacteroidales bacterium CF.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales.
OX NCBI_TaxID=1400053 {ECO:0000313|EMBL:AGY54336.1, ECO:0000313|Proteomes:UP000017642};
RN [1] {ECO:0000313|EMBL:AGY54336.1, ECO:0000313|Proteomes:UP000017642}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF {ECO:0000313|EMBL:AGY54336.1};
RX PubMed=24356833;
RA Tang S., Edwards E.A.;
RT "Complete Genome Sequence of Bacteroidales Strain CF from a Chloroform-
RT Dechlorinating Enrichment Culture.";
RL Genome Announc. 1:e01066-13(2013).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC ECO:0000256|RuleBase:RU003345}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP006772; AGY54336.1; -; Genomic_DNA.
DR AlphaFoldDB; U5Q741; -.
DR STRING; 1400053.BRDCF_p1709; -.
DR KEGG; bacc:BRDCF_p1709; -.
DR HOGENOM; CLU_005391_3_1_10; -.
DR OrthoDB; 9762913at2; -.
DR Proteomes; UP000017642; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07136; ALDH_YwdH-P39616; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036492};
KW Reference proteome {ECO:0000313|Proteomes:UP000017642}.
FT DOMAIN 12..424
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 209
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT ECO:0000256|PROSITE-ProRule:PRU10007"
FT ACT_SITE 243
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 453 AA; 51384 MW; 750E21A59C22C565 CRC64;
MNLQSLFQSQ QAFFRSQQTK DIDFRKRQLL KLKGLLKANE EKLYGAIYED FAKSKFDTYT
TELSIMYSEI EYFLKNISRL SKQEKIKTNM INFPGKSRIY YEPLGCTLII GAWNYPYQLT
LLPVITAVAA GNTCIIKPSE LPANTMRVMA EIINDNFPPE FLYVVQGGVE ETTELLKFPY
DKIFFTGSTK VGRIVYEAAA RNLTPVTLEL GGKSPVIVAK SADLRIAAKR IVWGKFLNAG
QTCIAPDYLL VEECVRERLL DLITERIESS NYVDGSENYV KIINKRNFER VVKMIDSTKV
VYGGGFNQET LYIQPTIMDN VGWSDAVMQE EIFGPLLPVI GFTDFEEVLD KILSFEKPLS
AYLFSNEEKQ KSSFVNKLSF GGGCINDTIM HIANDKLPFG GVGNSGIGNY HGKFGFMAFS
HQKPVFEKPN KGEFDLKYPP YTDSKKKWVD KLV
//
