ID V4LZM4_EUTSA Unreviewed; 543 AA.
AC V4LZM4;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
GN ORFNames=EUTSA_v10020467mg {ECO:0000313|EMBL:ESQ49319.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ49319.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ49319.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000032,
CC ECO:0000256|RuleBase:RU361203};
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962};
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|ARBA:ARBA00008723,
CC ECO:0000256|RuleBase:RU361203}.
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DR EMBL; KI517408; ESQ49319.1; -; Genomic_DNA.
DR RefSeq; XP_006407866.1; XM_006407803.1.
DR AlphaFoldDB; V4LZM4; -.
DR STRING; 72664.V4LZM4; -.
DR EnsemblPlants; ESQ49319; ESQ49319; EUTSA_v10020467mg.
DR GeneID; 18025153; -.
DR Gramene; ESQ49319; ESQ49319; EUTSA_v10020467mg.
DR KEGG; eus:EUTSA_v10020467mg; -.
DR eggNOG; KOG1378; Eukaryota.
DR OMA; WGRFMQN; -.
DR OrthoDB; 5485592at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 2.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR039331; PPA-like.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR InterPro; IPR025733; Purple_acid_PPase_C_dom.
DR PANTHER; PTHR22953; ACID PHOSPHATASE RELATED; 1.
DR PANTHER; PTHR22953:SF96; PURPLE ACID PHOSPHATASE 15; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361203};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361203};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT CHAIN 28..543
FT /note="Purple acid phosphatase"
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT /id="PRO_5005148481"
FT DOMAIN 74..186
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 198..410
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 476..522
FT /note="Iron/zinc purple acid phosphatase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
SQ SEQUENCE 543 AA; 61739 MW; C7C87076F0D2D9AA CRC64;
MAFHCDSITF LGLPLLLFFC LLSPASSSDD YIPTTLDGPF VPVTVPLDTS LRGKAIDLPH
TDPRVRRHVT GFEPEQISLS LSSDHDSIWV SWITGEFQIG KNVKPLDPTT IDSIVQFGTL
RHSLSHEAKG HSLVYSQLYP FDGLLNYTSG IIHHVRITGL KPSTVYYYRC GDPSRHAMSK
IHHFRTMPIS RPSSYPGRIA VVGDLGLTYN TTDTISHLIH NSPDLVLLIG DVSYANLYLT
NGTSSDCYSC SFPETPIHET HQPRWDYWGR FMESLTSKVP FMVVEGNHEI ELQVENKTFE
AYSSRFAFPF KESGSSSTLY YSFNAGGIHF VMLGAYIDFD KSGEQYEWLK KDLAKFDRSV
TPWLVVSWHP PWYSSYTAHY REAECMKEAM EELLYSYGTD IVFNGHVHAY ERSNRVYNYE
LDPCGPVYIV IGDGGNREKM AIEHADEPGK CPEPLATPDP AMGGKFCGWN FTTSGKFCWD
RQPDYSALRE SSFGHGILEM KNETWALWTW YRNQDSSSKV GDQIYIVREP DRCPRHNRLV
NHC
//
