ID W0J7R5_9BACT Unreviewed; 990 AA.
AC W0J7R5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00022419, ECO:0000256|HAMAP-Rule:MF_00595};
DE Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305, ECO:0000256|HAMAP-Rule:MF_00595};
GN Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN ORFNames=OPIT5_23600 {ECO:0000313|EMBL:AHF92744.1};
OS Opitutaceae bacterium TAV5.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae.
OX NCBI_TaxID=794903 {ECO:0000313|EMBL:AHF92744.1, ECO:0000313|Proteomes:UP000003813};
RN [1] {ECO:0000313|EMBL:AHF92744.1, ECO:0000313|Proteomes:UP000003813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TAV5 {ECO:0000313|EMBL:AHF92744.1};
RX PubMed=25744998;
RA Kotak M., Isanapong J., Goodwin L., Bruce D., Chen A., Han C.S.,
RA Huntemann M., Ivanova N., Land M.L., Nolan M., Pati A., Woyke T.,
RA Rodrigues J.L.;
RT "Complete Genome Sequence of the Opitutaceae Bacterium Strain TAV5, a
RT Potential Facultative Methylotroph of the Wood-Feeding Termite
RT Reticulitermes flavipes.";
RL Genome Announc. 3:0-0(2015).
CC -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC for the tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003670,
CC ECO:0000256|HAMAP-Rule:MF_00595}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC Evidence={ECO:0000256|ARBA:ARBA00001071, ECO:0000256|HAMAP-
CC Rule:MF_00595};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_00595};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC {ECO:0000256|ARBA:ARBA00008346, ECO:0000256|HAMAP-Rule:MF_00595}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP007053; AHF92744.1; -; Genomic_DNA.
DR AlphaFoldDB; W0J7R5; -.
DR STRING; 794903.OPIT5_23600; -.
DR KEGG; obt:OPIT5_23600; -.
DR eggNOG; COG2352; Bacteria.
DR HOGENOM; CLU_006557_2_0_0; -.
DR OrthoDB; 9768133at2; -.
DR Proteomes; UP000003813; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR HAMAP; MF_00595; PEPcase_type1; 1.
DR InterPro; IPR021135; PEP_COase.
DR InterPro; IPR022805; PEP_COase_bac/pln-type.
DR InterPro; IPR018129; PEP_COase_Lys_AS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR30523:SF6; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR Pfam; PF00311; PEPcase; 1.
DR PRINTS; PR00150; PEPCARBXLASE.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR PROSITE; PS00781; PEPCASE_1; 1.
PE 3: Inferred from homology;
KW Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300, ECO:0000256|HAMAP-
KW Rule:MF_00595};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00595};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|HAMAP-Rule:MF_00595};
KW Pyruvate {ECO:0000313|EMBL:AHF92744.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003813}.
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 73..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 192
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT ECO:0000256|PROSITE-ProRule:PRU10111"
FT ACT_SITE 649
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00595"
SQ SEQUENCE 990 AA; 108030 MW; 02F431365C57753F CRC64;
MARRTLAAAS ASTTSAFSES EKPRRKTSSA LGDLARLRDE VRFLGSVLGE VIREVEGEAT
FATVERLRTL AKARRGRAGG GRDSRHARES HAVRDGAGDQ LDKAVAALTP VEAFNQAMAF
TLYFELVNLA EENFRVQLLR LRRAERSANP AAPAQRESFD AALAELRASG VGPAELQELL
DRIGIELVFT AHPTESKRRT LLTKLQRLAL ILRQRNPQAT ADTAGLAAPS PASASDGVRD
PESVAKIRRE VASLWLTDRS RVERPGVNDE ARTGLWYFNT TLYDVLPRLQ ADLERALSLH
YPGVRAPSRW LTFGSWIGGD RDGNPNVTAA VSAGILVLHR RLAVEKLAAA TRELSRTLTV
SDRRDAVTPE LRRLLRENRH LSPHVDELGS RYPHEPYRLL LAGLGARLAK AAEEGRDGTT
LLGGPVADES CLREDTPREV FGAIRRSLEA GRGALLAEGE LKDAAHVLDV FGLHTARLDI
RQHSGPHEAA VAELLEVPGV AGEGEGAAAA PVKNYARLDE AARRQVLARA LATAKPLDAL
QRSELSAATR NVLDPLVLAA LTSVKFGSGA LGIYIISMTD DVSDVLEVAL IMRLAGADLP
IAPLFETLDD LNRAPDILAQ LFAHPAYAGL LEARARHQHV MLGYSDSNKD CGYLTANWAL
YQAQETIVAA CQASGVRVTL FHGRGGSIAR GGGPAARAIL AQPAGLRDGG IRITEQGEVL
STRYHDRDLA HRILEQMAYG VLLGAHAARN VQPPAAAWVQ AMETMSEAGF AAYRKLVHDD
PEFLQFWKQA TPIDEISNLK LGSRPSYRRA TQSVSDLRAI PWVFSWMQSR FNFPGWYGLG
SALEAVLRRG AAGRKLLRTM HAGWPFFRTL IDNAELTMRK ADMGIARLYA SLVEDEGVRE
RMLRALADEF ARAERAILAI TGRKQLLARE PVLLRSVELR NPYIDPLNYL QVEMLRRLRA
GGLSKADEEA VRAVVELTIN GISGGLKNTG
//
