ID W0RMW6_9BACT Unreviewed; 545 AA.
AC W0RMW6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Alpha-amylase {ECO:0000256|RuleBase:RU361134};
DE EC=3.2.1.1 {ECO:0000256|RuleBase:RU361134};
GN ORFNames=J421_4128 {ECO:0000313|EMBL:AHG91665.1};
OS Gemmatirosa kalamazoonensis.
OC Bacteria; Gemmatimonadota; Gemmatimonadetes; Gemmatimonadales;
OC Gemmatimonadaceae; Gemmatirosa.
OX NCBI_TaxID=861299 {ECO:0000313|EMBL:AHG91665.1, ECO:0000313|Proteomes:UP000019151};
RN [1] {ECO:0000313|EMBL:AHG91665.1, ECO:0000313|Proteomes:UP000019151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KBS708 {ECO:0000313|EMBL:AHG91665.1,
RC ECO:0000313|Proteomes:UP000019151};
RX PubMed=24699952;
RA Debruyn J.M., Radosevich M., Wommack K.E., Polson S.W., Hauser L.J.,
RA Fawaz M.N., Korlach J., Tsai Y.C.;
RT "Genome Sequence and Methylome of Soil Bacterium Gemmatirosa
RT kalamazoonensis KBS708T, a Member of the Rarely Cultivated Gemmatimonadetes
RT Phylum.";
RL Genome Announc. 2:e00226-14(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in
CC polysaccharides containing three or more (1->4)-alpha-linked D-
CC glucose units.; EC=3.2.1.1; Evidence={ECO:0000256|RuleBase:RU361134};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC {ECO:0000256|ARBA:ARBA00008061, ECO:0000256|RuleBase:RU003615}.
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DR EMBL; CP007128; AHG91665.1; -; Genomic_DNA.
DR AlphaFoldDB; W0RMW6; -.
DR SMR; W0RMW6; -.
DR STRING; 861299.J421_4128; -.
DR KEGG; gba:J421_4128; -.
DR PATRIC; fig|861299.3.peg.4183; -.
DR eggNOG; COG0366; Bacteria.
DR HOGENOM; CLU_006462_2_4_0; -.
DR InParanoid; W0RMW6; -.
DR Proteomes; UP000019151; Chromosome.
DR GO; GO:0004556; F:alpha-amylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043169; F:cation binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd11316; AmyAc_bac2_AmyA; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR006046; Alpha_amylase.
DR InterPro; IPR022567; DUF3459.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR045857; O16G_dom_2.
DR PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10357:SF179; NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR Pfam; PF11941; DUF3459; 1.
DR PRINTS; PR00110; ALPHAAMYLASE.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU361134};
KW Glycosidase {ECO:0000256|RuleBase:RU361134};
KW Hydrolase {ECO:0000256|RuleBase:RU361134};
KW Reference proteome {ECO:0000313|Proteomes:UP000019151}.
FT DOMAIN 49..436
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
SQ SEQUENCE 545 AA; 59970 MW; E3BF3F6427DB5ADD CRC64;
MAATGAPRSP LHAPRSLFRW LWLALAATTL APPADSQVPT WTRGATCYEI FVRSFYDSDG
DGIGDLNGLT QKLDYVQRLG ARCIWLMPVA ESPSYHGYDV SDYYRVEKDY GTNDDFKRLV
AAAHGRGIKV LVDMVLNHTS SEHPWFQAAL RDTASPYRAW YRWSQGGPGA PGPWAGSQPW
HKSPVRDEWY YGLFWVGMPD LNYVRTPVLD EAKRIARFWM RDMGVDGFRL DAVPYLVEEP
GRAQNSPGTH RVLHTYGDYV RSLGGYTVGE VFFPTDTLLS YYPDQLTGYF AFEIADSLIA
GVRRGDARGV LAPALRLQQA VRPAERFSPF LRNHDQPRTR TELGGDVAKA KVAALLLLTL
PGLPYVYYGE EIGMLGAKPD PRIRTPMQWS ASHAAGFTRG TPWERLADDS LAMTVEAQER
DSSSLLSLYR RLIHLRASDA ALASGTLAPL VASDDAVAAY VRRAGDRVVL VVANLDSTAR
RGVTLSAATG TLPPGRWAVR ALLGNGPAAP LVVRADGSVQ GYVPLDTLAP RAGVVLELVR
ATRRP
//
