KEGG   Thermoproteus tenax: TTX_0202
Entry
TTX_0202          CDS       T01641                                 
Symbol
leuA-3
Name
(GenBank) 2-isopropylmalate synthase 3
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
ttn  Thermoproteus tenax
Pathway
ttn00290  Valine, leucine and isoleucine biosynthesis
ttn00620  Pyruvate metabolism
ttn01100  Metabolic pathways
ttn01110  Biosynthesis of secondary metabolites
ttn01210  2-Oxocarboxylic acid metabolism
ttn01230  Biosynthesis of amino acids
Module
ttn_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:ttn00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    TTX_0202 (leuA-3)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    TTX_0202 (leuA-3)
Enzymes [BR:ttn01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     TTX_0202 (leuA-3)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer GDH_ACT3 PEP_mutase
Other DBs
NCBI-ProteinID: CCC80881
UniProt: G4RMT7
Position
190269..191873
AA seq 534 aa
MGVHPTYAGDRVQVLDTTLRDGAQGASVSFTLKDKIAIALKLDELGVDYIEGGWPYSNPK
DYEFFRSIKEYGLRAKVAAFGSTRRKGVRPDKDENLNSIVKADVQAAVIFGKSWTLHVRE
VLGTTWEENLAMISESVEYLKSHGMEVVYDAEHFFQGYQEDPEMALASIEAAWRAGASVI
ALADTNGGTPPSEIYRIVQEVKRRFPAMPLGAHMHNDIGCAVANTLMAVAAGARHVQGTI
NGIGERTGNADLTAVLPTLELKMGFKVLREEPPQIKFGRLREVSRLVYEVLNVQPNPYQP
YVGDFAFAHKGGVHADAVMKVPRAYEHIDPELVGNRRVIVVSEMAGGASLALRLSELGIS
AEKRDPRLKAALEEIKRLEREGYSFDVGPASAELIVLKHLGLYREMFKLKEWRVITGPTS
ASYAVVKVAIGGIDYVEGAEGVGPVHAVDMALRKALAKAFPDLQRVALRDYKVILPTLVK
NTESVVRVTVEFSDGSRVWRTVGVSTNVVEASVKALADGLDYYLQVASLAVAKI
NT seq 1605 nt   +upstreamnt  +downstreamnt
atgggggttcaccccacttatgccggggatcgggtccaagttctcgacacgacgttgaga
gacggcgcacagggcgccagcgtctccttcacgctaaaggacaagatagccatcgcgttg
aagctcgacgagttgggcgtagactatatagagggaggctggccctactcgaatcctaag
gactatgaattcttcaggtctatcaaggagtacggcctcagagccaaggtggcggccttc
gggagcactaggaggaagggcgtgaggcccgacaaagacgagaatttaaactccatagtg
aaggccgatgtccaggccgcagtgatattcggcaagtcctggacgctccacgtgagggag
gtgttgggcactacgtgggaggagaacttggctatgatatcggagagcgtcgagtacctc
aaatcgcacggcatggaggtggtctacgacgccgaacacttcttccaaggataccaggag
gacccggagatggctctggcctccatagaggccgcgtggagggccggggccagcgtgatc
gctctagctgacaccaacggcggaactccccccagcgagatctacagaatagtccaggag
gtgaagaggaggttccccgccatgcccctcggcgcccacatgcacaacgacataggatgc
gccgtagccaacacgctgatggctgtggcggcaggcgccagacatgtgcaggggactata
aacgggataggcgagcgcactggaaacgccgatctcacggccgtcctgccaacgttggag
ctgaagatgggcttcaaggtcttgagggaggagcccccgcagatcaagttcggcagattg
agggaggtatcgcgcctagtgtacgaggtcttgaacgtgcagccgaacccctaccagccc
tacgtgggcgacttcgcctttgcccacaagggcggagtccacgcagacgccgtcatgaag
gtcccaagggcgtatgagcatatagaccccgagctggtcggaaacaggagagtcattgta
gtctctgagatggccggaggggctagcttggcgctcagattgagcgagttgggcatatct
gccgagaagagggatccgaggctcaaggcagctctggaggagataaagaggctggagaga
gagggctactccttcgacgtgggacctgcgtcggccgagctcatagtgttaaagcacttg
ggcctctaccgagagatgttcaagctgaaggagtggcgcgttatcaccggccccacgagc
gcctcatatgcagtggtcaaagtggccatcggggggatagactacgtcgagggcgccgag
ggcgtggggcctgttcacgcggtcgatatggctctgaggaaggcgctcgccaaggcgttc
ccagacctccagagggtcgctctaagggactataaagtcattctgccgacgctcgtgaag
aacaccgagagcgtagtcagagtcaccgtggagttctccgacggttcaagagtctggagg
acggtgggagtttcgacaaacgtcgttgaggcgtcggtcaaagcgctggccgacggcttg
gactactatctacaggtggcctccttggctgttgcaaaaatctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (25)   

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