KEGG   Tupaia chinensis (Chinese tree shrew): 102488839
Entry
102488839         CDS       T02978                                 
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase
  KO
K01930  folylpolyglutamate synthase [EC:6.3.2.17]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup00790  Folate biosynthesis
tup01100  Metabolic pathways
tup01240  Biosynthesis of cofactors
tup01523  Antifolate resistance
Brite
KEGG Orthology (KO) [BR:tup00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    102488839 (FPGS)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    102488839 (FPGS)
Enzymes [BR:tup01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.17  tetrahydrofolate synthase
     102488839 (FPGS)
SSDB
Motif
Pfam: Mur_ligase_C
Other DBs
NCBI-GeneID: 102488839
NCBI-ProteinID: XP_006154123
Position
Un
AA seq 590 aa
MSQARSHLRAALSLAAVSARGSTAGVMARRGLSARPAPQEPGMEYQDAVRMLNTLQTNAG
YLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTECILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWRLYHRLEETKVPWDGSCVSMPAY
FRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSALGIDHTSLLGDTVE
KIAWQKGGIFKHGVPAFTVLQPEGPLAVLRDRARQVSCPLYLCPPLEALEEGGPPLTLGL
EGEHQRSNASLALQLARCWLQQQDHQGIGELTASRPSLPRQLSLAPVFQPTAHMRRGLRE
TEWPGRTQVLRRGPLTWYLDGAHTTSSVQACVRWFRQALQGRVRPSGGPEVRVLLFNSTG
DRDPAALLKLLQPCQFDYAVFCPNLTEVSPMGSADQQNFTVTLDQVLLRCLEHQRHWSHL
DEQHTSPDLWSSPSLEPGGSASLLLASHPPMPSGASSLVFSCISHALQWISQGRDPVFQP
PPPPRGLLAHPVASSGASELREAAAIHVLAPPSLHLVGGVLKLLEPSLSQ
NT seq 1773 nt   +upstreamnt  +downstreamnt
atgtcgcaggcacggagccacctgcgcgctgctctgtccctggcagcggtgtccgcacgc
ggctcaacggctggggtcatggcgcggcgtggactgagcgcgcggcctgcgcctcaagag
cctggcatggagtatcaggatgccgtccgcatgctcaacaccctgcagaccaatgccggc
tacctggagcaggtgaagcgccagcggggcgacccccagacacagctggaagccatggaa
ctgtacctggcacggagtgggctgcaggtggaggacttggaccagctgaacatcatccac
gtcactgggaccaaggggaagggctccacctgtgccttcactgaatgcattcttcgaagc
tatggcctgaagacaggtttctttagctctccccacctggtgcaggtgcgtgagcggatc
cgcatcaacgggcagcccatcagtcccgagctgttcaccaagcacttctggcgcctctac
caccggctggaagaaaccaaggtgccctgggacggcagctgtgtctccatgcctgcctac
ttccgcttcctgaccctcatggcctttcacgtcttcctccaagagaaggtagacctggca
gtggtggaagtgggcattggcggggcctatgattgcaccaacatcatcaggaagcctgtg
gtgtgcggtgtctccgctcttggcattgatcacaccagccttctgggggacacggtggag
aagatcgcatggcagaaggggggcatctttaagcatggtgtcccggcctttactgtgctc
cagcccgaaggacccctggcagtgctgagggatcgagcccggcaggtctcttgccctctc
tacctgtgcccacccctggaagccctggaggaaggggggccgccactgaccctgggcctg
gagggagagcaccagcggtccaatgcttccttggccctgcagctggcccgctgctggctg
cagcagcaggaccaccagggcattggggagctgacggcctccaggccaagcctcccacgg
cagctgtccctggcaccagtgttccagcccacggcccacatgcggcgtgggctgagggaa
acggagtggccgggccggacgcaggtgctgcggcgcgggcccctcacctggtatctggac
ggcgcgcacaccaccagcagcgtgcaggcctgtgtgcgctggtttcgccaggcgctgcag
ggccgcgtgagaccaagcgggggtcctgaggtgcgtgtcttactcttcaactccaccggg
gaccgggacccggcggcccttctgaagctgctgcagccttgccagtttgactatgccgtc
ttctgccccaacctgacagaggtgtcacccatgggcagtgcagaccaacagaactttacg
gtgacgctggaccaggtgctgctccgctgcctcgaacaccagcggcactggagccacctg
gatgagcagcacaccagcccagatctctggagcagccccagcctggaacctggagggtcc
gcatccctgctgttggcgtcccacccacccatgcccagcggtgccagctcacttgtcttc
agctgtatctctcatgccctgcagtggatcagccaaggccgggaccccgtcttccagcct
cctcctcccccaaggggcctcctcgcccatcctgtggccagcagtggggccagcgagctc
cgagaggctgctgccatccacgtgctggccccgcccagcctgcacctggtgggtggtgtc
ctgaagctgctggagccctccttgtcccagtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (10)   
   RefSeq(pep) (10)   
DNA sequence (16)   
   RefSeq(nuc) (12)   
   GenBank (2)   
   EMBL (2)   
Protein domain (1)   
   Pfam (1)   
All databases (71)   

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