KEGG   Tupaia chinensis (Chinese tree shrew): 102475126
Entry
102475126         CDS       T02978                                 
Symbol
UGT1A8
Name
(RefSeq) UDP-glucuronosyltransferase 1-6
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup00040  Pentose and glucuronate interconversions
tup00053  Ascorbate and aldarate metabolism
tup00140  Steroid hormone biosynthesis
tup00830  Retinol metabolism
tup00860  Porphyrin metabolism
tup00980  Metabolism of xenobiotics by cytochrome P450
tup00982  Drug metabolism - cytochrome P450
tup00983  Drug metabolism - other enzymes
tup01100  Metabolic pathways
tup01240  Biosynthesis of cofactors
tup04976  Bile secretion
tup05204  Chemical carcinogenesis - DNA adducts
tup05207  Chemical carcinogenesis - receptor activation
Module
tup_M00014  Glucuronate pathway (uronate pathway)
tup_M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:tup00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    102475126 (UGT1A8)
   00053 Ascorbate and aldarate metabolism
    102475126 (UGT1A8)
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    102475126 (UGT1A8)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    102475126 (UGT1A8)
   00860 Porphyrin metabolism
    102475126 (UGT1A8)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    102475126 (UGT1A8)
   00982 Drug metabolism - cytochrome P450
    102475126 (UGT1A8)
   00983 Drug metabolism - other enzymes
    102475126 (UGT1A8)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    102475126 (UGT1A8)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    102475126 (UGT1A8)
   05207 Chemical carcinogenesis - receptor activation
    102475126 (UGT1A8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:tup01003]
    102475126 (UGT1A8)
Enzymes [BR:tup01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     102475126 (UGT1A8)
Glycosyltransferases [BR:tup01003]
 Others
  Hydrophobic molecule
   102475126 (UGT1A8)
SSDB
Motif
Pfam: UDPGT EryCIII-like_C Glyco_tran_28_C Glyco_transf_4
Other DBs
NCBI-GeneID: 102475126
NCBI-ProteinID: XP_006171216
Position
Un
AA seq 532 aa
MACHLHACRGASAGVFFLALCGLVAGDKLLVFPQDGSHWLSMKDIVEHLSDRGHDIVVLV
PEVNLLLRESKYYTRKIYTVPYDEEELKTRFRTFGNGHFAERSFLSAPLVEYRNNMNVVE
LCFINCQHLLKDQDTLDFLKEGKFDALFTDPAMPCGVILAEYLGLPSVYLFRGFPCSLEH
TFSRSPNPVSYIPRCYTKFSDHMTFPQRVGNFLVNWLEPFLFYCLYSKYEDLASEVLKRD
VHLPALYRKGSVWLLRYDFVFDYPRPVMPNMVFIGGTNCKKKKDLSQEFEGYINASGEHG
IVVFSLGSMVSEIPEKKAMEIAEALGKIPQTVLWRYTGSRPSNLAKNTILVKWLPQNDLL
AHPKTRAFITHSGSHGIYEGICNGVPMVMLPLFGDQMDNAKRMETKGAGVTLNVLEMTSE
DLANALKTVIFDKSYKENIMRLSSLHKDRPIEPLDLAVFWVEFVMRHKGAPHLRPAAHDL
TWYQYHSLDVMGFLLAIALTVAFVTFKICACGFRKCFGKKGRAKKSHKSKAH
NT seq 1599 nt   +upstreamnt  +downstreamnt
atggcctgccatcttcatgcatgtcggggagcttctgctggggttttcttcttggccctt
tgtgggctggttgcaggtgacaagctgctggtgtttccccaggatggaagccactggctt
agtatgaaggacatagttgagcatctcagtgacagggggcatgacattgtggtgctagtg
ccagaagtcaatttgcttttgagagaatccaaatactacacgaggaaaatctacacagtg
ccttacgatgaagaagagctgaagacccggttccgcaccttcgggaacggtcacttcgcc
gagaggtcattcctgagcgctcctctggtggagtacaggaacaacatgaatgttgtcgaa
ctgtgcttcatcaactgccagcacctcctgaaggaccaggacacgctggatttcctcaaa
gagggcaagtttgatgctcttttcacagacccagccatgccctgcggtgtgatcctggct
gagtacctgggcctgccctccgtgtacctcttccggggcttcccgtgttcgttggaacac
acgttcagcagaagtcccaaccctgtgtcctacatccccaggtgctacaccaagttctca
gatcacatgacctttccccagcgcgtgggcaacttcctcgtgaattggttagagcccttt
ctgttctattgtctgtactccaagtatgaagacctcgcgtcggaagttctcaagagagat
gtgcacttgcctgccctgtaccgaaagggctctgtttggctgttaagatatgactttgtg
tttgattatcccaggccagtcatgcccaatatggtcttcattggagggaccaactgcaaa
aagaagaaagatctgtctcaggaatttgaaggctacattaatgcctctggagaacatgga
attgtggttttctctttgggatctatggtctcagagattccagagaagaaagctatggaa
atagctgaagctttgggcaaaatacctcagacggtcctgtggcggtatactggaagccgc
ccatcaaaccttgcgaagaatacgatacttgtcaagtggctaccccaaaatgatctgctt
gctcacccaaagactcgtgccttcatcacgcattccggctcccacggcatttatgaagga
atatgcaatggtgtcccgatggtgatgctgcccttgttcggtgaccagatggacaacgcc
aagcgcatggagaccaaaggagctggagtgaccctgaatgtccttgaaatgacttctgaa
gatttagcaaatgctctaaagacagtcatctttgacaaaagctacaaggaaaacatcatg
cgcctctccagtcttcacaaggaccggcccatagagcctctggacctggctgtgttctgg
gtggagttcgtgatgaggcacaagggggcgccccacctgcgccctgcagcccacgacctc
acttggtaccagtaccactccctggatgtgatgggcttcctcctggccatcgcactgacg
gtggccttcgtcacctttaaaatctgtgcctgtggctttcggaaatgcttcggtaaaaaa
gggcgggcgaagaaaagtcacaaatccaaggcgcactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (15)   
   KEGG PATHWAY (13)   
   KEGG MODULE (2)   
Chemical substance (40)   
   KEGG COMPOUND (40)   
Chemical reaction (21)   
   KEGG ENZYME (1)   
   KEGG REACTION (20)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (4)   
   Pfam (4)   
All databases (105)   

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