ID A0A010R7E4_9PEZI Unreviewed; 1155 AA.
AC A0A010R7E4;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=TOG domain-containing protein {ECO:0000259|SMART:SM01349};
GN ORFNames=CFIO01_07040 {ECO:0000313|EMBL:EXF73624.1};
OS Colletotrichum fioriniae PJ7.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum acutatum species complex.
OX NCBI_TaxID=1445577 {ECO:0000313|EMBL:EXF73624.1, ECO:0000313|Proteomes:UP000020467};
RN [1] {ECO:0000313|EMBL:EXF73624.1, ECO:0000313|Proteomes:UP000020467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PJ7 {ECO:0000313|EMBL:EXF73624.1,
RC ECO:0000313|Proteomes:UP000020467};
RA Baroncelli R., Thon M.R.;
RT "The genome sequence of Colletotrichum fioriniae PJ7.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Microtubule binding protein that promotes the stabilization
CC of dynamic microtubules. Required for mitotic spindle formation.
CC {ECO:0000256|ARBA:ARBA00024889}.
CC -!- SUBUNIT: Interacts with microtubules. {ECO:0000256|ARBA:ARBA00011375}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}.
CC -!- SIMILARITY: Belongs to the CLASP family.
CC {ECO:0000256|ARBA:ARBA00009549}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXF73624.1}.
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DR EMBL; JARH01001050; EXF73624.1; -; Genomic_DNA.
DR RefSeq; XP_007602716.1; XM_007602654.1.
DR AlphaFoldDB; A0A010R7E4; -.
DR STRING; 1445577.A0A010R7E4; -.
DR KEGG; cfj:CFIO01_07040; -.
DR eggNOG; ENOG502QT5T; Eukaryota.
DR HOGENOM; CLU_004060_0_0_1; -.
DR OrthoDB; 1369289at2759; -.
DR Proteomes; UP000020467; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:UniProt.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024395; CLASP_N_dom.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR21567; CLASP; 1.
DR PANTHER; PTHR21567:SF9; CLIP-ASSOCIATING PROTEIN; 1.
DR Pfam; PF12348; CLASP_N; 2.
DR SMART; SM01349; TOG; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000020467}.
FT DOMAIN 3..232
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 283..518
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 902..1153
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REGION 226..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..836
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 892..911
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 575..595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..658
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1155 AA; 125455 MW; 4DF78671037B3978 CRC64;
MADKITEEQV DDLLKILRSE ASVDQKVQHV TGIKSGIKQH NVPDVLVPQV FDGLRTASTS
PHAVLVNAGF TALNHLLTRL SRQEPKYIAK DAKHTLPLVI DKLGDPKDKF RSLASQALTT
IYTAAPMDVE RSVKNVAMVG KNPRAKEASM HWLLYMHQEH GTQFRAYVPT LMELLEDADG
MVRDVAKSTV IELFRNAPNA AKSDLKRQLK NFNVRPAIEQ AIVKELAPTA ADRPKTPGLD
APAPAPRPKL AASVSSVASE RPVTPAPETR SEVEPSYANT QRELDDIFRE MMTYFEGRES
EQNWLKREES MTKLRRLIAG NVPEDFPDAF MLGLKGLLDG IIKAITSLRT SLSKEGCNLV
QDIAMTFGPG MDPLVELLMQ TFIKLAAATK KIASQQADTT VNIIIGKVTY NSRIMQHIWG
ACQDKNVQPR TYATGWLKTI LTKEAHHKSH IEHGGGLDLV EKCIKKGLND ANPGVRERMR
ATFWVFAKIW PSRADMLKDT LEPTAQKLLD KDPNNPNAPK REVEATRARP GLGLSKSTMG
TGKPTLRETM MAQKKATMAA SQKLPPRPGS AMANLSPARP QQATSSSSSG PAPSAKPTAS
GGMSVRPMRP TKRRPEMAAR PATAGPYSVR THDGPSAEAS SPENPKSRST TTRPKTEASP
RRAQSRPRAA TSHASPGAKS TLSKSVSSPR DSPRTSPAKP KRMQTTIPTS SPSRDNEDLT
LVVPSLGSLK STPTLDRRQR AATEEPTVPD FEADAPAEVS ADIPLPKAEP VQEASPEPVS
EPTPEPAEQS QAEPEDEGTV EAPSETSPEA PAAETEEAPV EEILEAPAEA AAGGLAPSPV
IEEMAKAEPE PVPTNGLKVF EDPFVDDGTT AGPDITTPVL EDKPVNEVAV PAPSNGFEAN
GTPETPEKAR QTSRLLDSGV TRVKAKSLDV HGFRKLQSII RDNKAVFTDE KFEALLRGLF
EYLESPLETL APERVQDVKA QIVARIKLLL KKERDNFQPH VSRGLESLVS TRSAYDSRTR
IVSGLELLAE ELVALGDPPE IVVVMTKLLQ SKQDTTIEGS RCLATGLHVL KELLDKRTGF
TPSDNELAQL AGLAGRCLES TDSGVRMGAV QLCVALHARI GDAPFWELIK GAKDDPKNLI
TYYIAKHQRE SSVGA
//
