ID A0A011N146_9PROT Unreviewed; 221 AA.
AC A0A011N146;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=UDP-N-acetyl-D-glucosamine 6-dehydrogenase {ECO:0000313|EMBL:EXI68581.1};
DE EC=1.1.1.136 {ECO:0000313|EMBL:EXI68581.1};
GN Name=wbpA_1 {ECO:0000313|EMBL:EXI68581.1};
GN ORFNames=AW08_00893 {ECO:0000313|EMBL:EXI68581.1};
OS Candidatus Accumulibacter adjunctus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Candidatus Accumulibacter.
OX NCBI_TaxID=1454001 {ECO:0000313|EMBL:EXI68581.1, ECO:0000313|Proteomes:UP000020218};
RN [1] {ECO:0000313|EMBL:EXI68581.1, ECO:0000313|Proteomes:UP000020218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-12 {ECO:0000313|Proteomes:UP000020218};
RA Skennerton C.T., Barr J.J., Slater F.R., Bond P.L., Tyson G.W.;
RT "Expanding our view of genomic diversity in Candidatus Accumulibacter
RT clades.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXI68581.1}.
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DR EMBL; JFAX01000004; EXI68581.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A011N146; -.
DR STRING; 1454001.AW08_00893; -.
DR PATRIC; fig|1454001.3.peg.1032; -.
DR Proteomes; UP000020218; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0047004; F:UDP-N-acetylglucosamine 6-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF1; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:EXI68581.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000020218}.
FT DOMAIN 56..160
FT /note="UDP-glucose/GDP-mannose dehydrogenase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03721"
FT DOMAIN 182..217
FT /note="UDP-glucose/GDP-mannose dehydrogenase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF00984"
SQ SEQUENCE 221 AA; 24634 MW; 6B4E4484D8F14C0B CRC64;
MFNTPSMIGL DYMRLRTATL SGSREKLLGR YAKQYAATAG YLRVLKDRQP TENVPTAMPR
PFTNGHELDF AHIQATGKSI APVLANRNLV IAESTLPIPT TPEFADWPPQ ARPRVSLPEQ
TAESADIHKA YFPERLLPSS SVHELAANDL VICSMTRTAT YMATPLAKTV VERDLVPTNA
PTAEMRKRAE TRFRDVKIGS ANELSIICDK MDINVWEHRG E
//
