ID A0A011NTC1_9PROT Unreviewed; 772 AA.
AC A0A011NTC1;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=ComEC family competence protein {ECO:0000313|EMBL:EXI67837.1};
GN ORFNames=AW08_01778 {ECO:0000313|EMBL:EXI67837.1};
OS Candidatus Accumulibacter adjunctus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Candidatus Accumulibacter.
OX NCBI_TaxID=1454001 {ECO:0000313|EMBL:EXI67837.1, ECO:0000313|Proteomes:UP000020218};
RN [1] {ECO:0000313|EMBL:EXI67837.1, ECO:0000313|Proteomes:UP000020218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-12 {ECO:0000313|Proteomes:UP000020218};
RA Skennerton C.T., Barr J.J., Slater F.R., Bond P.L., Tyson G.W.;
RT "Expanding our view of genomic diversity in Candidatus Accumulibacter
RT clades.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXI67837.1}.
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DR EMBL; JFAX01000008; EXI67837.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A011NTC1; -.
DR STRING; 1454001.AW08_01778; -.
DR PATRIC; fig|1454001.3.peg.1809; -.
DR Proteomes; UP000020218; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000020218};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 531..693
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 772 AA; 84773 MW; A8FDC381480AE5DE CRC64;
MRSNILAFAL GVGLLQLQEA LPAWPLLTVW PLVALPLLWP ACRRSRWGRV LALLASALFG
FSWAALLAAQ RLHDRLPAAW EGRDIQVVGV VAALPHGFER GERFAFDVES VETRAAVVPR
RIMLSWYHGW LEDEWRDGLQ IRPGERWRFT VRLKRPHGNA NPLAFDYEAW LFERGLRATG
YVRPQAAVER LDDFVVQPAY AIERLRDRLR RSFAAVLGDA AYSGILIALA VGDQQAIPGE
QWRLFRQTGV THLMSISGLH VTMVAALFGA LVGCLWRRSE RLLLAVPAQK AAIAGGWLAA
FAYALLAGFA VPAQRTVYML TVVALALWSG RHLGASRSLL LALLLVLLLD PWAVLAPGFW
LSFAAVALLF FVGTARLGSG RGWRATLAAW GATQWAVTIG TLPLLLLLFQ QFSLVSPLAN
AIAIPLVSFI ITPLALLFVV LPWPPLLLVA HALLDFLMSG LDWLAAWPMW EQPAPPLAAT
LLAVVGVIWL LLPRGFPARW LGLCLLLPAV FWPAARPAHG EAWVEVLDVG QGLAVVVRTA
GHSLLYDTGP LFSAESDAGQ RIIVPHLRAQ GVRRLDTLIV THRDKDHSGG VVAVEEALPI
GRRLSSVPEL QPEPCIDGQS WEWDGVRFAI LHPVAADYQR QAARSNNMSC VLQVSSAHGS
VLLTADIEAR DEQALLARGA GRLRSDVLLV PHHGSGTSST PPFIAAVGAR EAIIPVGYRN
RFQHPRADVV DRHAASRLWR TDRDGAVRVS LVAAGLSVSA YRNEYRRYWH GQ
//
