ID A0A011Q381_9PROT Unreviewed; 704 AA.
AC A0A011Q381;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=kinD {ECO:0000313|EMBL:EXI73004.1};
GN ORFNames=AW07_02936 {ECO:0000313|EMBL:EXI73004.1};
OS Candidatus Accumulibacter sp. SK-11.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Candidatus Accumulibacter.
OX NCBI_TaxID=1454000 {ECO:0000313|EMBL:EXI73004.1, ECO:0000313|Proteomes:UP000020226};
RN [1] {ECO:0000313|EMBL:EXI73004.1, ECO:0000313|Proteomes:UP000020226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-11 {ECO:0000313|Proteomes:UP000020226};
RA Skennerton C.T., Barr J.J., Slater F.R., Bond P.L., Tyson G.W.;
RT "Expanding our view of genomic diversity in Candidatus Accumulibacter
RT clades.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXI73004.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JFAW01000018; EXI73004.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A011Q381; -.
DR STRING; 1454000.AW07_02936; -.
DR PATRIC; fig|1454000.3.peg.2414; -.
DR Proteomes; UP000020226; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR014265; PrsK.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR02916; PEP_his_kin; 1.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EXI73004.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000020226};
KW Transferase {ECO:0000313|EMBL:EXI73004.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 487..689
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 704 AA; 77652 MW; BB119458E0EE288A CRC64;
MMDGKMAMIS AWSYGLAGVL AALLTLYLAS GRRSSARSGA MFLAVALCTV WGMLGLAFAL
TGQGIFLAGS LLADVLRFGG WYLFLIILMR PESADGAPAT AATGWLSALA VLLVVGGFVA
QAMAIFGVDL AGSAQRLALF VSLAMSVFGL VLVERLFRNV SPDFRWSIKP LCLGLGGVFL
FDLYVYSDAL LFNRIDADAF SIRGFAHALA LPLVALSAIR SHDWKRRLVM SQRAVLQSAT
LLIVGTYLLF MAAAGYYVRF FGGEWGRALQ LALLFAALLV LAVLTFSGSM RARLRVQVGK
HFFSYRYDYR EEWLRFTATL SSQGGFTSLG RHVVRGLADM VESPSGALWL KDPSGRFFAQ
AAFWNMPASP ATEDADSPLC RFLLDSGWVI NLEEYRSLPR RYDGLVVPSW LVEVPNAWLV
VPLTTGSELI AFVVLATART RIDVNWEVND LLKTAARQAG AFLGQMQASE ALLEVRKFDS
FNRMSAFVVH DLKNIIAQLS LMLKNAERHR DNPEFQKDML MTVEHSVERM RQLMMQLRQG
TTPLDGPRGI DLADVLRRIQ TAKSGQGREV ELSIEERLLA RGHEDRIERV IGHLVQNALD
ATERGGRVWV RMARQGDQAL VEVGDTGHGM SPDFVRERLF KPFQTTKPTG MGIGAYESFQ
YVHELGGRVS VDSAVDVGTQ VDLLLPLFEV GKARKSDELS GKHE
//
