ID A0A014PQV3_9HYPO Unreviewed; 1676 AA.
AC A0A014PQV3;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=GTPase-activator protein for Ras-like GTPase {ECO:0000313|EMBL:EXV00100.1};
GN ORFNames=X797_006893 {ECO:0000313|EMBL:EXV00100.1};
OS Metarhizium robertsii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=568076 {ECO:0000313|EMBL:EXV00100.1, ECO:0000313|Proteomes:UP000030151};
RN [1] {ECO:0000313|EMBL:EXV00100.1, ECO:0000313|Proteomes:UP000030151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 2575 {ECO:0000313|EMBL:EXV00100.1,
RC ECO:0000313|Proteomes:UP000030151};
RA Giuliano Garisto Donzelli B., Roe B.A., Macmil S.L., Krasnoff S.B.,
RA Gibson D.M.;
RT "The genome sequence of the entomopathogenic fungus Metarhizium robertsii
RT ARSEF 2575.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXV00100.1}.
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DR EMBL; JELW01000015; EXV00100.1; -; Genomic_DNA.
DR eggNOG; KOG2128; Eukaryota.
DR HOGENOM; CLU_000972_1_1_1; -.
DR OrthoDB; 12619at2759; -.
DR Proteomes; UP000030151; Unassembled WGS sequence.
DR GO; GO:0015629; C:actin cytoskeleton; IEA:UniProt.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR CDD; cd21206; CH_IQGAP; 1.
DR CDD; cd05127; RasGAP_IQGAP_like; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR000593; RasGAP_C.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR14149:SF14; PATTERNED EXPRESSION SITE; 1.
DR PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF03836; RasGAP_C; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM00015; IQ; 6.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF143885; RGC domain-like; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS50096; IQ; 8.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 293..399
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 1041..1257
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 94..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 188..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 722..775
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1676 AA; 191824 MW; 2EDC2D8BB73B742E CRC64;
MSFQSHRLRQ SRTADLAPPT SFTHNNISTS ISNINRFPST TSSSASSGYS STSDRSNVTQ
YTSASSDHGS PAGRKHKRGQ SDVLARARTF EAGAMNGFNT GPANPPATPT RQSVRPLPQA
PTTSPRSPAQ GASPRSSLRH DRGQSIDIGK LSLSQYDGPA APPTSPPRPL PMRPNSMLLT
RSDSILQAKT PMPHGSSPQG SHTTHIGRPD LELLGRSTTR ELRTLSRLAE SDVAEDFTIT
SSAQEVVGLR GRRRLQRTDK HTGSRSAKSG GYGWEGRNWM DKQRQFLQAY EYLCHIGEAK
EWIEDVTQKT LPPIVELEEA LRDGVTLANV VEALNPQRHF RVFHHPKLQF RHSDNIAIFF
RYLDEVELPD LFRFELIDLY EKKNIPKVIY CVHALSWLLF RKGIVDFRIG NLVGQLEFEH
HELEAMQKGL DMLGANMPSF GNMGADFGVP EPEPVETEEE RIDRELGENE ESIVDLQAQI
RGALLRLRLG NKMQQFWDEE HWLIDLQSRI RGDFTRQIMS YRLQMRRSAT LTQSAARGFL
VRERLRKSDA FWKAHEPEIL ELQSMIRANQ VRDEVRDLLY SLDGCKGPVR EIQAVSRGFL
VRKNLAAQQQ ETKKTSGHVE RLQALARGMG LRARISKDLQ LLGGQAGTVA SLQAAARALL
TRTQIDREQQ QLRALGPKWE ALQGAIRGKL VREKQEAYKV EAQKHELNIG KLQAVIRAGA
VRREVARKLD ALEESKEEIL SLQSGARGMM ERLKVAALQQ ELNRHEARIT GLQAQVRGYI
GRNQHHALLD ELKSHNEATA EFQAILKAMM TRAGVDDLLT ELEEEEESIV ALQAATRGFM
VRAKFEEKKR YFNENMKKVI KIQSFVRAKV QGEAYKSLTT GKNPPVNAVK NFVHLLNDSD
FDFNEEVEFE RMRKTVVQQV RQNEMLEQYI DQLDIKIALL VKNKITLDEV VRHQHNYGGN
SMGLLANSTI TSANQFDLKA LNKSSRKKLE SYQQLFFSLQ TQPQYLARLF KHLREQGTSE
KEYKRIELLV MSLFGYAQKR REEYYLLKLV ARAIREEVEG CRAIQEYIRG NYFWPKLLGN
YTRSPRDRKY LRSLLGPLIR DNIVEDPALD LESDPMQIYR SAINNEELRT GRPDLRPLDV
PREVAIRDPE TRRLFIDHLR DLREICDQFF LSLEEMAHKM PYGLRFLSSQ MFQALCQHFN
REPQENLLQL VANWIWKFYL QPALTQPEQL GVIEKSLSPL QKRNLSEVAK VIGQVASGRP
FGGENIYLQP LNNFVTDSIQ RMRQILQNLI SVADAESTFG VDEFNDLYAK NKPTLYIKMT
DVFAIHNLVA SELPFMCPTR DDVLREIIQD LGNAKSNENE MNAAGSSDIQ MFLTPKLHNV
QDPEEDVKSL FMETKRCVLY IIRVQTGANL LEILVKPIYE EDEEKWQTVL HDDFSNDGNT
RGAYSDTNMV DVTRMTYYEL KRTALENIMR LEQMGRISKQ NYYQDVLNAI ASDIRTKSRR
RVQRQRELEG VRLTLTNLAE KAKYLEQQRK SYDDYIEQAM VTLQNKKGKK KFLLPFTKQY
NHQRELERSG RVPKFGSYKY SARTLSEKGV LVSWAGLSDR EWDKINITIS CDEVGVFAIE
GSRGHIQMPG ASALVPIEDM LQAQFESHQF MNLFEGNLKL NVNLLLHLVY KKFYGT
//
