ID A0A016SFL1_9BILA Unreviewed; 556 AA.
AC A0A016SFL1;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN Name=Acey_s0235.g3175 {ECO:0000313|EMBL:EYB89136.1};
GN ORFNames=Y032_0235g3175 {ECO:0000313|EMBL:EYB89136.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB89136.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB89136.1}.
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DR EMBL; JARK01001571; EYB89136.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016SFL1; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR47324:SF1; PROTEIN IRG-7; 1.
DR PANTHER; PTHR47324; PROTEIN IRG-7-RELATED; 1.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT DOMAIN 370..551
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 294..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..322
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 556 AA; 60049 MW; 16578370AB3A5038 CRC64;
MSSSSLNAPK FSEISNTKIS VNLVYVSSKK CGSAPPDSAM FPLARLAYTS GGNVIFTDSE
NLTKYLHAYL PTVYSKSILA NPTLHSNFAC PVNKDWHVQV DSNTASFFVA TTSTFGSVGV
IDPKDRIIMP TVLYKVGRTK LYRINSSNSS GVYTLSLASP GACYAHVYTG NKAKVFASFA
LTSPNDSNGS HNDGEFLSPC RGVANIATFH LHAAHVKESL LFVEGYNPET NLKLFHSELH
RRINCSFEYY SAPFVCNTET LGLAVHGVDE AGQPFKRQEI FFCRTRTIEV STTAATNKPP
TIASSSSKAV STKASTSPST KPITKPPSKP TTRPPTKSTT NSRPSTNHPL ASSTKPTAGT
TAAPSSLRFD VVFLVDVSQD AKDLLNDMIK FAGSLMSAFE VSQDNARAAV VSVGALDSNA
IGSLNAISSQ EMLDQYLKML FQYDEFDEQG QDIVGALRIT VFDDFLKSGY RKDINNHLII
YVTATTNFNE DPQAVAQKIL SDGTYGIVTV GYGPQATDKK ALQRISGGEK CTFSANNKDS
LYGHAPAIQA LIKEAR
//
