ID A0A016SJN7_9BILA Unreviewed; 850 AA.
AC A0A016SJN7;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN Name=Acey_s0218.g2421 {ECO:0000313|EMBL:EYB90567.1};
GN ORFNames=Y032_0218g2421 {ECO:0000313|EMBL:EYB90567.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB90567.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB90567.1}.
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DR EMBL; JARK01001554; EYB90567.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016SJN7; -.
DR STRING; 53326.A0A016SJN7; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF269; ABC TRANSPORTER CED-7; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 148..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 540..763
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 850 AA; 95684 MW; B39835675ECFCF0A CRC64;
MSAISIPLAG TYYKICSLGI GGSASHKWCK YVQIVNEHVE DAKTGELNGC QLRFELPRSQ
QERFPGLFAH LEDKKQSLRI ESFGLSVNAL EEAYLKVMRM GEVPSREADE DVFQDNSVLE
LQEGFFARII QQLQYIWLKR IIEISHNISL IVNQILLPIA LAILVGWTMR KKSVNIAKHH
LEHHNVPDIS LNRIKSGRVV VLDPSHNTEK RRLLEKVMKK YPHIQITHHR SSKWAEHWPK
EFPWAVLGVI IRSQGAIANG SEAYYWLLPS YLYYKEQTLF HLISDVEYAA GKLQMHVSFT
RMIADTASMT LMVLSPFLVF IAAVLMNSSF IPSLIEERVF HFKHQQFLAG LSPLLFWVAT
IIWDSGVIVV VAGIITLVMK IFKLAVTRMF MPLICAYCVA MLPMVYVLSL LIDTPGVAKS
VSILYQIGSA ALGFVMLFQG GKKKFTHAFP SFAVVMSFMK ELFSTNIPKL SVTERETYES
LLLHGVIFVV VLIVHELHFE KLLLKTVCKK TYIERSEVPD GADIIEERER VENNISDFAL
AVQDLTKYHG VTCAVKKTTY GIKEKDCFGL VGASGAGKTS TFDVITGLRS ANSGTVFIGD
EFVNRTQGIG YCPQFDAMLP RLSCRQNMMV IAALNGYKYP KKVVDEMLRF LDLTEHSSKA
FSRCSGGQRR RVGIGVALMN PSKLAILDEP TAGIDPKTRH QIWSLLKKMR ASGKAIVLSS
HSMEECEALC SRIGILVRGR LVAIGASQTL KTRHADNFFL HMSMTSVTHK DLVVSTVLTT
FPSGNLMTRR EDALTLKFKI RQRKEDKVST LYEKAQKMAS SLPLKEFMLI QASLEDVLEI
LNEQYSGKAL
//
