ID A0A016SN59_9BILA Unreviewed; 504 AA.
AC A0A016SN59;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Cytochrome b561 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0202.g1780 {ECO:0000313|EMBL:EYB91769.1};
GN ORFNames=Y032_0202g1780 {ECO:0000313|EMBL:EYB91769.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB91769.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SIMILARITY: Belongs to the insect defense protein family.
CC {ECO:0000256|ARBA:ARBA00008501}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB91769.1}.
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DR EMBL; JARK01001538; EYB91769.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016SN59; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd08760; Cyt_b561_FRRS1_like; 1.
DR Gene3D; 1.20.120.1770; -; 1.
DR InterPro; IPR006593; Cyt_b561/ferric_Rdtase_TM.
DR InterPro; IPR005018; DOMON_domain.
DR PANTHER; PTHR45828; CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE; 1.
DR PANTHER; PTHR45828:SF33; REELIN DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF03351; DOMON; 1.
DR SMART; SM00665; B561; 1.
DR PROSITE; PS50939; CYTOCHROME_B561; 1.
DR PROSITE; PS50836; DOMON; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..504
FT /note="Cytochrome b561 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001486963"
FT TRANSMEM 217..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..172
FT /note="DOMON"
FT /evidence="ECO:0000259|PROSITE:PS50836"
FT DOMAIN 176..393
FT /note="Cytochrome b561"
FT /evidence="ECO:0000259|PROSITE:PS50939"
FT REGION 409..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..457
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 504 AA; 55908 MW; B5A71C5FE4ED3C65 CRC64;
MRRLTKDQIW CFLIASLTLI YGKGTFNNAT CGTKKGCFVS SESNGMAVSY EVLSPESIRF
ELTMKTTATS SLYLAVGFSK DDKMGLDNVI ECSALTGQPL SMKFSYNPAL KNARIPGEET
IRPQYFQNET ATISDGMMYC AATVNVSGWG PSNGQVFTYK ENQRYFLLLA AGSAITSGLT
QHSVTAVSSS RLLTDYGAQG STGLSSTVRK RLIKAHAILM ILSWFFFVPT AVMFARFLRA
SWPTMKPGGL LIWFHVHRTF NTIAILLSIA SFVCILTANS WEWTGPGSQS SDWGKKHTMV
GIFALCLCWI QPFVSAMRCN PAHPRRQFFN WVHRGIGVIA MILATTTVCI AAIHFLSIWP
HKISQTTLSL MPLVILLIMS AVFLCIDKFI DVDELNLSKL YQEPMIGSKE EAGSQEPLIE
PNEEKPLGSQ KASGSEGSEK SSADQKTQDS ADVANEKKEK VSLRKILLST GATNPTITRL
RRSHRHGIDN DYIIDFRWNW GIIH
//
