ID A0A016SRC9_9BILA Unreviewed; 741 AA.
AC A0A016SRC9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=polyribonucleotide nucleotidyltransferase {ECO:0000256|ARBA:ARBA00012416};
DE EC=2.7.7.8 {ECO:0000256|ARBA:ARBA00012416};
GN Name=Acey_s0186.g1073 {ECO:0000313|EMBL:EYB93090.1};
GN Synonyms=Acey-BE0003N10.1 {ECO:0000313|EMBL:EYB93090.1};
GN ORFNames=Y032_0186g1073 {ECO:0000313|EMBL:EYB93090.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB93090.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SIMILARITY: Belongs to the polyribonucleotide nucleotidyltransferase
CC family. {ECO:0000256|ARBA:ARBA00007404}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB93090.1}.
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DR EMBL; JARK01001522; EYB93090.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016SRC9; -.
DR STRING; 53326.A0A016SRC9; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0004654; F:polyribonucleotide nucleotidyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd11364; RNase_PH_PNPase_2; 1.
DR Gene3D; 3.30.230.70; GHMP Kinase, N-terminal domain; 2.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR001247; ExoRNase_PH_dom1.
DR InterPro; IPR015847; ExoRNase_PH_dom2.
DR InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR012162; PNPase.
DR InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR InterPro; IPR015848; PNPase_PH_RNA-bd_bac/org-type.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR03591; polynuc_phos; 1.
DR PANTHER; PTHR11252; POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE; 1.
DR PANTHER; PTHR11252:SF0; POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR Pfam; PF03726; PNPase; 1.
DR Pfam; PF01138; RNase_PH; 2.
DR Pfam; PF03725; RNase_PH_C; 2.
DR PIRSF; PIRSF005499; PNPase; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF55666; Ribonuclease PH domain 2-like; 2.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 2.
DR PROSITE; PS50126; S1; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 656..727
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
SQ SEQUENCE 741 AA; 80206 MW; 7C6071EA5C5299A2 CRC64;
MSLLHGAILK AACAQRLVLL SRCLKHSVAV CVGDGGPLTL TTGHMARFAS GAVVASAGDS
AVLSTCVFRA STSESYPGQD FVPLLVDFKQ SAAAVGKIPT NYLRRELGQT DADILASRVI
DRSLRPLFPP GWTNETQIVV KPLAVEEEAD VVLLGLNAAA SALHLSAVPW LGPTAAVRVG
LVEDKFVLNP SRSILKQSSL DLLLTGCGDR RTVMIEMNGE QVPTEKLEEA IDVGLDAVGE
ILTAMDELRA QAGKEKAEFS LSKFPQDLED EVRALCEERL YYILSDPTHD KVSRDNAIKE
VGCDVVESIK DCDPSMVQAI FRHLTKKALR DLVLDHNMRC DGRGITEFRP ITISVDVFKR
LHGSSLFQRG QTQVMSTVTF DSPAAAFHSD SISQILGSQR KKMFMLHYEF PSYATNEISS
SRGANRRELG HGALAEKALK HVIPKEFPYS IRLACQVLES NGSSSMASAC GGSLALLDAG
VPLSASVAGV AVGLITDKDS KRPHKVLTDI SGIEDYAGDM DFKIAGSSQG FTAMQLDVKI
PGLTRQQLTE AFTSGKAGID HVLDKMAVMI DRPREGFKPT VPVIESMRLD AYKRQALFRA
GGMHAKTIEA ETGVKISHED DAHISLFAPN KRLLEDAKAL MTKLLSETDE PEFAFGQMVS
AEVVELLERG AMLRLAGSGR PVFVPNSQLH SVPIRHSSAS GLQVGQKTTV QWLGRDADTG
QIRLSRKTIA SVDLPSRTPR K
//
