ID A0A016TUD5_9BILA Unreviewed; 1445 AA.
AC A0A016TUD5;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Band 4.1 domain-containing protein {ECO:0000259|SMART:SM00295};
GN Name=Acey_s0076.g1048 {ECO:0000313|EMBL:EYC06415.1};
GN ORFNames=Y032_0076g1048 {ECO:0000313|EMBL:EYC06415.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC06415.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC06415.1}.
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DR EMBL; JARK01001412; EYC06415.1; -; Genomic_DNA.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR019748; FERM_central.
DR PANTHER; PTHR24118:SF99; CHARON; 1.
DR PANTHER; PTHR24118; POTE ANKYRIN DOMAIN; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00373; FERM_M; 1.
DR SMART; SM00248; ANK; 4.
DR SMART; SM00295; B41; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 3.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT REPEAT 1..31
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 73..105
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 106..140
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1088..1365
FT /note="Band 4.1"
FT /evidence="ECO:0000259|SMART:SM00295"
FT REGION 639..674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..940
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1005..1034
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..655
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 775..806
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 820..844
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 856..872
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..916
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1445 AA; 160826 MW; EEDFE4D167D6555B CRC64;
MNTLHMAVAH KQRDIVELLL RSGYDPNSPA SCHCKGNCTA TGNIPLSSII PRTQSMTPEL
CSTCLQLRVA SIVDQTPLGV AVRTQSSELI ALLIAYGADV NLGDEDGNTP LMLAVRDSPI
CWPCLHTLIF FGAQVEQKNI RGICPLDLAP ELKKLQHTCT EELFKIACAG CDNDSSSKPT
LAPIFKNWNQ LQVDSASQGE RSLNKMPLSS KPSAAPSIST CSMLDTNSAK ESARRKSLIS
LHLHRKSKST KEYPAVDSIT WEQAWELLKR MACNPECLDM VVGSLLKFSS QMESVPQNVN
REAFDAHLGG LLHKLISTAI EEYESSTPSY KKQKKTRLAG LFSQITSFCY TFIHKSGTSR
LFSALNALNK IIDAGLVHDL FPYNDVAFHS SRLLNRSHVF EADDYSLNQE SCSSNCEEGS
TVDHVFIYGA GYRDNSALPS PTQTPVRHKS DLANSFAEMD PSQGEDVFPF EERFRSRLSE
RHQLRSLVAL LEPTLEPQLL CLLLQCLALI ALDPATHVTF VDVQIDDVLI QMLLPADDWY
YTNHSTKYGL FVKYHAARVL IYVGMGDRVG NRVNLFTITA NENFPTPSKA SAHPNEDDYI
CETCATPRVM TAFSRSAMSV EGILLKILTE VAELAKQGTN LSTSEPITEE SPSRTSPPAL
MEHESDARAT EKNDGRNENL MCHALISLEQ LEAHLCKLGL VFDSVLLLRL LLHKLSWDLG
LVAKKRVAVV DQAHKSSVDP RAHSSLSLGN NIRCFGKSMS FDRREDGKGD KKFLSVEQGS
RSSRRVRIRR SSSVEVIRPK RLSSGAKDSR HRGRRKRLGT DTSSGSNRSK KTTSSSSSVQ
KHFPRYIQSL FRGRMGTDPC KRHPRRDSNE SNTSDSDAVL EFTRKLQNYP PNRRETQRQM
FRSCDQPDSQ QGRQSGHGFL PELEIHGASP PRSPGCPSRI SFEESHLLFD SRRPSSPQAI
PGVPQIEIRR PSALSQFEFG YFVNSPELIG SEMSDCAPLL LMGSTTQVGS RKSSDETSLG
GWSSRASSVM SQRSSRSSAG LRLSTFSGGA SIASDNSGPF LFSFVLRKRA STIGTRIPIP
RRALSRSSGD SLRVPDRESP LHLATTAEMN PDFQCVRQLI LNLLNIYTGR NANVASTMRE
CSELFGQVLN SPQHPSIKSW CAEILNIVGA QIAQEDHSTV ECHEQLNDEY LDLQDQVISA
SLPCPKEEAA YLASIQLCVE EQWPSNKRVQ TIRRHLLKGQ FGRIRDLAQK IMVTPWEVDA
NLYCTPSRIP SDSQSGAHQV IETIPHRSRT PALLRCITNP DGLISEEMQA QCLPLDLRGD
RRTIKLVQER KRKLFHSKVY DDEVAMKKLY IQTAKRLAAF GCKVFQVKEL LHGRTLRKTL
RLLCLSSSSL SLLDGTTKLV LKRQHASTLQ QWRVGGGVSK HQLLLEFRGT KWQLIGEYVS
HLNAL
//
