ID   A0A016UUU0_9BILA        Unreviewed;       844 AA.
AC   A0A016UUU0;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=PDZ/DHR/GLGF domain protein {ECO:0008006|Google:ProtNLM};
GN   Name=Acey_s0027.g1572 {ECO:0000313|EMBL:EYC18532.1};
GN   Synonyms=Acey-magi-1 {ECO:0000313|EMBL:EYC18532.1};
GN   ORFNames=Y032_0027g1572 {ECO:0000313|EMBL:EYC18532.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC18532.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYC18532.1}.
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DR   EMBL; JARK01001363; EYC18532.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A016UUU0; -.
DR   STRING; 53326.A0A016UUU0; -.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   CDD; cd00992; PDZ_signaling; 4.
DR   CDD; cd00201; WW; 2.
DR   Gene3D; 2.20.70.10; -; 2.
DR   Gene3D; 2.30.42.10; -; 4.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR001202; WW_dom.
DR   InterPro; IPR036020; WW_dom_sf.
DR   PANTHER; PTHR10316:SF40; LD27118P; 1.
DR   PANTHER; PTHR10316; MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED; 1.
DR   Pfam; PF00595; PDZ; 4.
DR   Pfam; PF00397; WW; 2.
DR   SMART; SM00228; PDZ; 4.
DR   SMART; SM00456; WW; 2.
DR   SUPFAM; SSF50156; PDZ domain-like; 4.
DR   SUPFAM; SSF51045; WW domain; 2.
DR   PROSITE; PS50106; PDZ; 4.
DR   PROSITE; PS01159; WW_DOMAIN_1; 2.
DR   PROSITE; PS50020; WW_DOMAIN_2; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT   DOMAIN          61..94
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   DOMAIN          93..126
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   DOMAIN          197..263
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          311..374
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          496..578
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          607..689
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          150..190
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          386..436
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..179
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   844 AA;  90946 MW;  F93E6C1132257F10 CRC64;
     MRRRFRLLLF RKVKSEDHGA KRGFLSKSAS VDQWAGGHLY GTPRPEECYE GTAMVSSANK
     GPLPPNWEIG YAENGDKYFI DHNSGTTTWD DPRDLPPGWE QVDDPEYGTF FVDHINKKTQ
     YERPGTSTTT TMPRYDALPT TAAGGGGHMA NGITTNGHQH SPQHQQGNKG RQSVVPSGGG
     NPYFTRDPSQ LRGEMVTTTI IKGTKGLGFT LIGNDASSKG DEFIQVKSVL PGGPAAEDGV
     LRAGDVLVRV NGELLLGASQ SDACRIFVNI PVGDPVAIQV CRGYPLLLDP SNRIITENVY
     QTGGRSRDLH DIEIVKGPEG FGFTIADSAT GQRVKKILYP EQCANLLEGD TIVELDGRNV
     RAIPHTHLVD MLRECPIGHR GRLVVRRSSP KHRSRTPAAE FRYGEQPRAT PLPNVSPRSK
     TPAPVPGGRH EAEPTTMPAA RAQTLQRQPN VSQADVWDGA SFGARMKPSS TTLGFATPNY
     MPLSAFQFNK PNDLITVNLI RKPSGFGFRL LGGSETNTLL TVGQVVPGGA AAEDGRMQEG
     DEIVEIDGRN VEGVSHAEAV SLLEHAAHNK HVKLVVRRPR MGADPLRRQS LHVERPGGAI
     AGSGEYDVCL TRNETDGFGF IIISSLNRNG STIGQILENS PAEKCGRLKV GDRVVAVNGI
     DILNLSHGEI VGLIKASGLT VRLTIAPPIP DGSPLASSTL NRTSIPNMSY APSPPSSFIP
     PPPVFQNGGL YATVGRNTNY STYSQPSMTP APFSYTNGSV LKTTSQFSSY PDGGRPIYTT
     SHINGQLNGI SLHDPVPPEQ QPSCESLLLA LRESGVFDTY SESADIDAIE SLTPSDSPTL
     TTRR
//