ID A0A016VBR6_9BILA Unreviewed; 560 AA.
AC A0A016VBR6;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=CDP-alcohol phosphatidyltransferase {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0014.g2363 {ECO:0000313|EMBL:EYC24168.1};
GN ORFNames=Y032_0014g2363 {ECO:0000313|EMBL:EYC24168.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC24168.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SIMILARITY: Belongs to the CDP-alcohol phosphatidyltransferase class-I
CC family. {ECO:0000256|ARBA:ARBA00010441, ECO:0000256|RuleBase:RU003750}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC24168.1}.
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DR EMBL; JARK01001350; EYC24168.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016VBR6; -.
DR STRING; 53326.A0A016VBR6; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.20.120.1760; -; 1.
DR InterPro; IPR000462; CDP-OH_P_trans.
DR InterPro; IPR043130; CDP-OH_PTrfase_TM_dom.
DR InterPro; IPR048254; CDP_ALCOHOL_P_TRANSF_CS.
DR InterPro; IPR014472; CHOPT.
DR PANTHER; PTHR10414:SF41; CHOLINE_ETHANOLAMINEPHOSPHOTRANSFERASE; 1.
DR PANTHER; PTHR10414; ETHANOLAMINEPHOSPHOTRANSFERASE; 1.
DR Pfam; PF01066; CDP-OH_P_transf; 1.
DR PROSITE; PS00379; CDP_ALCOHOL_P_TRANSF; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023209};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003750};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 100..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 560 AA; 62239 MW; 00CE53993D7D4201 CRC64;
MSESSENSGV DGSPLWLNNV VEHVEIFWKK VKMGCSPGSR LCGFWSWYIE ADSLATEQEL
KRLGEHKYSA VDNSWLDELC MKKWWEYVVT WCPMWVAPNL ITLVGLVINL ITVLILSSFS
YSATEPAPAW AYAQAALGLF FYQTLDAIDG KQARRTGSSS PLGELFDHGC DSMTQVFVTL
NICYAMSLGH MPNGVMFVSI VSVVMFYAAH WSTYCTGQLR FSKFDVTEAQ MSVIAVLLTT
CIFGNSFWDT NLVAGWKLRH VVLGTSMIGS IYQILGYVNV IIHGGVGKNG STIAGTSVIF
PLFPLLMVVL PFCMIYSRAE TSVYDDHITL FMLCFGAVGA KATNRLVIAH MSKSELRLWD
WIYLGPLSLM LNQYYNTVFD ELMLLRIVTL TPNGRRQGGG TAARAPWLSA ALQRACWAET
QRKTDTSRFP AASGCAADNQ GARVGVPLFV YDRLEFTVQS LIHSPIHSNE DIDVQKRKKN
VAHSGSNCHV GEHTPISAVF VNSQPSIVST TGKMVGMTPE VYCYASLLVY CTVVCRQFCE
YFNIYCFTLD ARSPSTKKST
//
