ID   A0A016VTR9_9BILA        Unreviewed;       398 AA.
AC   A0A016VTR9;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=GIY-YIG domain-containing protein {ECO:0000259|PROSITE:PS50164};
GN   Name=Acey_s0004.g1725 {ECO:0000313|EMBL:EYC30711.1};
GN   ORFNames=Y032_0004g1725 {ECO:0000313|EMBL:EYC30711.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC30711.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYC30711.1}.
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DR   EMBL; JARK01001340; EYC30711.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A016VTR9; -.
DR   STRING; 53326.A0A016VTR9; -.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   CDD; cd00304; RT_like; 1.
DR   Gene3D; 3.40.1440.10; GIY-YIG endonuclease; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR21301; REVERSE TRANSCRIPTASE; 1.
DR   PANTHER; PTHR21301:SF12; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF82771; GIY-YIG endonuclease; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT   DOMAIN          288..378
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000259|PROSITE:PS50164"
SQ   SEQUENCE   398 AA;  45641 MW;  70A9D63817B96D89 CRC64;
     MLVLHGREIE TYGLGRARVM TLVKECLTCN VFKWSGRYFS QIRGLAMGQR LAPVLAICYM
     SKIEGPVLSR QPLLYCRYID DCCVITSTQS EMDECFRLLN EQSQYIKLTR ETPHEGWLPF
     LNTQLKISNG MVHVKWYRKE SCKNIVVHAR SAHPMTVKRA VIRNMFKTAI EVSSGEAERQ
     ESTRLASVIA RENGYFSRGQ QHRRARTSSK TNEYQNKLPL CIPFISDRIS DAIKKCLARS
     QLQNDVVLIN IPNDNIKRQL VRNRLYDRSC ITKNCVTCPY GRSGDCAKTG VVYQIECLSC
     HAIYIGETGR PLHVRINEHL ASKRRESLIK PLGKHRHEDH SGNDFDVACT ILAHEPEISA
     RKALEAFWIS ARNPRMNNRN EHISITSDLM PFLPLCEL
//