ID A0A016VY54_9BILA Unreviewed; 750 AA.
AC A0A016VY54;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=FF domain protein {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0003.g1479 {ECO:0000313|EMBL:EYC32256.1};
GN Synonyms=Acey-ZK1098.1 {ECO:0000313|EMBL:EYC32256.1};
GN ORFNames=Y032_0003g1479 {ECO:0000313|EMBL:EYC32256.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC32256.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC32256.1}.
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DR EMBL; JARK01001339; EYC32256.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016VY54; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IEA:InterPro.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 1.10.10.440; FF domain; 5.
DR InterPro; IPR002713; FF_domain.
DR InterPro; IPR036517; FF_domain_sf.
DR InterPro; IPR039726; Prp40-like.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR11864; PRE-MRNA-PROCESSING PROTEIN PRP40; 1.
DR PANTHER; PTHR11864:SF0; PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST); 1.
DR Pfam; PF01846; FF; 3.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00441; FF; 5.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF81698; FF domain; 5.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS51676; FF; 4.
DR PROSITE; PS01159; WW_DOMAIN_1; 2.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT DOMAIN 94..127
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 152..179
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 251..309
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 322..376
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 386..449
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT DOMAIN 468..530
FT /note="FF"
FT /evidence="ECO:0000259|PROSITE:PS51676"
FT REGION 74..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 122..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 308..335
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 440..478
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 84..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..211
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 671..685
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..701
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..722
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 733..750
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 750 AA; 87232 MW; 9AEC74969B6263A3 CRC64;
MSFYYSNDPR ISTEMLPGFG FPILNVNPGL VAGQQILLNA NALQRVMVST ANPLVSVPLP
AAAPVSGRPT PMLVPPGMAG EEGNSDSPQA QAPTTQECPW TKHETAEGRV YYYNKITKES
SWNKPDELKT PQERQERSTP TTSSSSSSNV IWKEYKTPEG RAYYYNTVTK ETTWTKPESM
TAAAATTEAA KTTTEEVKKE KTEEPKEESE MEKAMKATLA SMTVPLPAET NIATPEQAVE
VAADDNEQDL KKRQAERFRD LLRDKYNEGK ITSTCNWEHA VKHIQSDPRF RILTKVSEKK
QLFNAWKVQR QKEERDEKRL AIKKAKEDLE KWLQDHPKMK PGLKYMRARE IFNKEPVWQA
VHEDDRQDIF REALAYVTKR DADLNRETRK RNIKALAEIL ESMDQITYKT TWAQAQRLLI
ENPQFADDTT LQSMDKEDAL IVFEEHIRQA EKEHAEIKEA EERRIKRQER KVREDFQKFL
QELHKKGELT SMSLWSSLYP VISSDPRFDA MLTQDGSSTP LDLFKFYVEE LKEQYGQDRR
VIKDILNDQK KVVQVDTTFE EFSKWVTSAE KGLLVDHGNM KLCYNSLVEK AESKEREAER
EEARKKRRQE SEFRHLLRAQ QPVVDANTEW SAVRGKIEKE KAFLVIESEE LRVKYFEDYK
RSLSEACTHH HSVSKKKKKD KKKKGRKSDK ESDSESDPKE KRKRKKHSKE DRDSDDEKER
SRKSRKRKRS RSRSSSRSDD EKKRRDSDSD
//
