ID   A0A016W5E4_9BILA        Unreviewed;       358 AA.
AC   A0A016W5E4;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|Pfam:PF00078};
GN   Name=Acey_s0001.g316 {ECO:0000313|EMBL:EYC34233.1};
GN   ORFNames=Y032_0001g316 {ECO:0000313|EMBL:EYC34233.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC34233.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYC34233.1}.
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DR   EMBL; JARK01001337; EYC34233.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A016W5E4; -.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR19446:SF415; REVERSE TRANSCRIPTASE-RELATED PROTEIN; 1.
DR   PANTHER; PTHR19446; REVERSE TRANSCRIPTASES; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT   DOMAIN          181..334
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|Pfam:PF00078"
SQ   SEQUENCE   358 AA;  41375 MW;  B1BB7A0B57503E9A CRC64;
     MDNVPEDLRK LLWEEDFLRH QTPNMHIYYS QEVISMACEN GLTAIIGDGV HKLNPMNTPN
     RMDKGQLYVI HGVVSGGIEV PPLYAITRHK NVATYRTIFG RLREAIPDDR LKIVLDFEKG
     MWFKWDVREL RTTSAAEAFH SKLRKMVSRR THPMLEELLE CLQELTILAL GRLLHVQDGD
     KEDLENCRPI TRLPVLYKVF TRCILTCIRR TLDEAQPVER AGFRRKFSIL DHIITCCRLI
     EVAREYQEAL VLAFIDYKKA FDSVEPAKVR KALEEQSVEM RYSKVLNEYF SVCTTVFRPF
     HDDIEVSLGK GVRQGDPVSL NLFSACSESV IRNCDWSTFG IPIDGKRPIH LASQMTWC
//