ID A0A016WGW0_9BILA Unreviewed; 742 AA.
AC A0A016WGW0;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0000259|PROSITE:PS50262};
GN Name=Acey_s0690.g1562 {ECO:0000313|EMBL:EYC38856.1};
GN ORFNames=Y032_0690g1562 {ECO:0000313|EMBL:EYC38856.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC38856.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC38856.1}.
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DR EMBL; JARK01000290; EYC38856.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016WGW0; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd00637; 7tm_classA_rhodopsin-like; 2.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 2.
DR InterPro; IPR019424; 7TM_GPCR_Srsx.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24246:SF27; ADENOSINE RECEPTOR, ISOFORM A; 1.
DR PANTHER; PTHR24246; OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR; 1.
DR Pfam; PF10320; 7TM_GPCR_Srsx; 2.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 2.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 2.
PE 4: Predicted;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 110..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 552..574
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 594..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 642..663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 683..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 123..376
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT DOMAIN 442..698
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 722..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 742 AA; 83670 MW; FB631794EC6024E6 CRC64;
MIQNASNVLR AGVSGSCDKI VAVTAVRHLV FVFELLADCE SPRHADSDGT HKMAQTAFES
VFGERFCGFP VDNHVYVYHY YYMKASTISD DPRDMVKHIQ EDPNSLLHPL YVYIVEGAIA
AALNVPLTIA MLATPKLRTR REFQVITGLA ATDAVFGLAF VISGVSRIHV MRQYCSTAMC
EIPLTPRWKC STLLYVQLIT IAFQLQGVLL LAVAVDRLLA VITPIKYLQF NVKYTFVLAA
GPYTLVAVAT VTNVLIVQND RTLVSPFCFI SFAVYPGFHD YIILLRIFCV ISSASIYIVI
VAHLNKHLSR VSAWSREQRS LRRSTFTVGL TTVNAVVFLL VPDVIVYFDI LDWSQSYSAV
LYSLSMANVI LNALILVFRH REIIHSFKRF VFVILFRRSP KAKNTVMVLS TNYSLDMNDE
DPRTIVKLLF LYIAEGAIAA ALNIPLMVAT LTNNSLRTRR EYQVIIGICF VDAVFGIAFV
LTAINRLEII QENFYTGIPQ VPRCVCSTRY YVHLLTIAYQ LQGVLTITVA TDRFLAVMTP
IRYLKFGTQY TVTILAGPYL YVAICTVINA VITLQDDTPV SSFCLTVTAV SPTFYYYMLL
LRISCVFISA LIYVVIIAHL YKHFARIEKM QASSRESSQF RSIRRSTITI GLSTVNAVLF
LLLPDVIKYI GVFDYSRSNV TTLYSLSMTN VVLNAFIFAY RHKEIMENFK HLMCTLLRRR
KPDDPQTSND AGKVLPNRKA FD
//
