ID A0A016WTH5_9BILA Unreviewed; 486 AA.
AC A0A016WTH5;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE AltName: Full=ATP:glycerol 3-phosphotransferase {ECO:0000256|ARBA:ARBA00043149};
GN Name=Acey_s0503.g2635 {ECO:0000313|EMBL:EYC43094.1};
GN Synonyms=Acey-R11F4.1 {ECO:0000313|EMBL:EYC43094.1};
GN ORFNames=Y032_0503g2635 {ECO:0000313|EMBL:EYC43094.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC43094.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC43094.1}.
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DR EMBL; JARK01000103; EYC43094.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016WTH5; -.
DR STRING; 53326.A0A016WTH5; -.
DR UniPathway; UPA00618; UER00672.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR005999; Glycerol_kin.
DR NCBIfam; TIGR01311; glycerol_kin; 1.
DR PANTHER; PTHR10196:SF69; GLYCEROL KINASE; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT DOMAIN 6..235
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 246..436
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 486 AA; 53419 MW; CA47E16A6C5138FF CRC64;
MTGLHGKALA NECIEVRQLF PNPGWVEMDP IEIIETVKEC IVQVVDKLEQ LGISIDEIKS
VGIANQRETT IVWDSKTGEP LHNAIVWLDS RTSDLAEQSI ARTKSRSKDE FKQKTGLPIH
PYFSALKIKW LMENVDAVKK ASQEGRLMFG TVDTWLIWKL TGEHATDVSN ASRTLLLDLW
KRKWSCQLCE FFGIPPEILP QIRSSAEVFG HFFDGPLQGI PIAGCLGDQQ AAMVGHNCLK
RGDTKNTYGT GTFMLCNIGS NPTISKNGLL TTVGFQFGPN SPVVFALEGS GSIGGNVVRF
LRDNFNFIKS AKEMEPICRS VGTTEGVFFV PCFTGLYTPY WDPTARGTIL GMTQVTTKAH
ICLAALRAVA YQSAEMIEAV EQDLGDTKIT TIKVDGGMTA NVLFNEIQAE IIGKVIKTPK
ITEISGWGAA VAGGIGAQQF SLDAFSSREA PAVTYMPHSD EHRRSADLQR WKEAVKRARG
WAESAK
//
