ID   A0A017HRB9_9RHOB        Unreviewed;       484 AA.
AC   A0A017HRB9;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   13-SEP-2023, entry version 40.
DE   RecName: Full=Phospholipase D {ECO:0000256|ARBA:ARBA00018392};
DE   AltName: Full=Choline phosphatase {ECO:0000256|ARBA:ARBA00029594};
GN   ORFNames=Rumeso_01661 {ECO:0000313|EMBL:EYD76703.1};
OS   Rubellimicrobium mesophilum DSM 19309.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Rubellimicrobium.
OX   NCBI_TaxID=442562 {ECO:0000313|EMBL:EYD76703.1, ECO:0000313|Proteomes:UP000019666};
RN   [1] {ECO:0000313|EMBL:EYD76703.1, ECO:0000313|Proteomes:UP000019666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19309 {ECO:0000313|EMBL:EYD76703.1,
RC   ECO:0000313|Proteomes:UP000019666};
RA   Fiebig A., Goeker M., Klenk H.-P.P.;
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Could be a virulence factor. {ECO:0000256|ARBA:ARBA00003145}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Secreted
CC       {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYD76703.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AOSK01000041; EYD76703.1; -; Genomic_DNA.
DR   RefSeq; WP_037277196.1; NZ_KK088521.1.
DR   AlphaFoldDB; A0A017HRB9; -.
DR   STRING; 442562.Rumeso_01661; -.
DR   PATRIC; fig|442562.3.peg.1644; -.
DR   HOGENOM; CLU_038053_1_1_5; -.
DR   Proteomes; UP000019666; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR   CDD; cd09110; PLDc_CLS_1; 1.
DR   CDD; cd09112; PLDc_CLS_2; 1.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR   InterPro; IPR022924; Cardiolipin_synthase.
DR   InterPro; IPR027379; CLS_N.
DR   InterPro; IPR025202; PLD-like_dom.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR   PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR   PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR   Pfam; PF13091; PLDc_2; 2.
DR   Pfam; PF13396; PLDc_N; 1.
DR   SMART; SM00155; PLDc; 2.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR   PROSITE; PS50035; PLD; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW   Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019666};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EYD76703.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        29..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          212..239
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
FT   DOMAIN          397..424
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
SQ   SEQUENCE   484 AA;  54298 MW;  76E81B3EF437D956 CRC64;
     MSLFTLGVTI YFVAAAAYIV SENRRPQSAF AWLFLFLTLP VGGLVIYILF GRMRGGVGRT
     RKLVRQDEGR QRDGVRGAAQ DEHDRAMERF ASRPPLVRQM ANLAHAACGA LVTTSNHVEV
     LEDASAKYPR LLADLEAARG TIHLQYYIWR PDSLGMRLMS LLEAKVAQGV KVRIIYDPVG
     SFGIKTAIYI RRMRARGIEM WPSSPLWRVH TISYRNHRKI AVIDGRIGYT GGMNIGLEHL
     DPARVYGRQD YREWRDTHLR ITGMAVRSLQ RVFTIDWENA TGEKLSGPEH FPPLAEGEVE
     DRQPVQLVLS GPDSEWRAVR QQYFGMIAAA RERVRVRTPY FILDASLAEA LKTAALSGID
     VSVMVADGGP DQRLVYWAAQ TYLVEIATAG VEVLLYEGGF LHAKTVVTDG WVASVGSGNW
     DIRSFSINYE LNALVYDTAV AAELEAAYER DRAHCRVFDP DAYRAGPRLL RFRDSLARLV
     SPLL
//